EARLY ULTRASTRUCTURAL CHANGES OF THYMOCYTES IN T-2 TOXICATED MICE
1993 Volume 6 Issue 1 Pages 109-112
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1993 Volume 6 Issue 1 Pages 109-112
Subcellular changes of mouse thymocytes after T-2 intoxication were observed for up to 48 hours after injection (HAI). The following changes were observed mainly in cortical lymphocytes at 8 and 16HAI: (1) nuclear projections, (2) nuclear macrocleft, and (3) characteristic features of apoptosis. Conclusively, it is suggested that apoptosis is partially involved in the early development of thymic lesions by T-2 toxin.
