Table 1Combinations of Multimorbidity (N=1,006)
Combination of multimorbidity |
Total |
Young and middle-aged adults |
Older adults |
1st Disease |
2nd Disease |
3rd Disease |
n (%) |
n (%) |
n (%) |
Hypertension |
Diabetes |
Hyperlipidemia |
263 (26.1) |
63 (33.2) |
200 (24.5) |
Hypertension |
Diabetes |
Arthritis |
178 (17.7) |
14 (7.4) |
164 (20.1) |
Hypertension |
Hyperlipidemia |
Arthritis |
173 (17.2) |
28 (14.7) |
145 (17.8) |
Hypertension |
Arthritis |
Lumbar pain |
34 (3.4) |
2 (1.1) |
32 (3.9) |
Hypertension |
Hyperlipidemia |
Angina |
33 (3.3) |
10 (5.3) |
23 (2.8) |
Hypertension |
Arthritis |
Angina |
29 (2.9) |
1 (0.5) |
28 (3.4) |
Hypertension |
Arthritis |
Osteoporosis |
28 (2.8) |
1 (0.5) |
27 (3.3) |
Hypertension |
Diabetes |
Angina |
25 (2.5) |
9 (4.7) |
16 (2.0) |
Hypertension |
Arthritis |
Disc herniation |
24 (2.4) |
6 (3.2) |
18 (2.2) |
Diabetes |
Hyperlipidemia |
Arthritis |
21 (2.1) |
9 (4.7) |
12 (1.5) |
Hypertension |
Hyperlipidemia |
Crebral infarction |
18 (1.8) |
5 (2.6) |
13 (1.6) |
Hypertension |
Diabetes |
Stroke |
17 (1.7) |
1 (0.5) |
16 (2.0) |
Hypertension |
Arthritis |
Stroke |
15 (1.5) |
0 (0.0) |
15 (1.8) |
Hypertension |
Diabetes |
Lumbar pain |
13 (1.3) |
1 (0.5) |
12 (1.5) |
Hypertension |
Hyperlipidemia |
Spinal stenosis |
13 (1.3) |
5 (2.6) |
8 (1.0) |
Hypertension |
Diabetes |
Crebral infarction |
12 (1.2) |
2 (1.1) |
10 (1.2) |
Hypertension |
Diabetes |
Disc herniation |
12 (1.2) |
3 (1.6) |
9 (1.1) |
Hypertension |
Hyperlipidemia |
Gout |
12 (1.2) |
5 (2.6) |
7 (0.9) |
Hypertension |
Hyperlipidemia |
Disc herniation |
12 (1.2) |
8 (4.2) |
4 (0.5) |
Hypertension |
Hyperlipidemia |
Osteoporosis |
12 (1.2) |
1 (0.5) |
11 (1.3) |
Hypertension |
Arthritis |
Crebral infarction |
12 (1.2) |
3 (1.6) |
9 (1.1) |
Hypertension |
Hyperlipidemia |
Allergic rhinitis |
10 (1.0) |
8 (4.2) |
2 (0.2) |
Hypertension |
Hyperlipidemia |
Rheumatoid arthritis |
10 (1.0) |
2 (1.1) |
8 (1.0) |
Hypertension |
Arthritis |
Ischemic heart disease |
10 (1.0) |
0 (0.0) |
10 (1.2) |
Hypertension |
Arthritis |
Spinal stenosis |
10 (1.0) |
0 (0.0) |
10 (1.2) |
Hypertension |
Arthritis |
Frozen shoulder |
10 (1.0) |
3 (1.6) |
7 (0.9) |
Total |
|
|
1,006 (100.0) |
190 (100.0) |
816 (100.0) |
Table 2General and Medical related Characteristics of Participants (N=1,006)†
Characteristics |
Categories |
Total (N=1,006) |
Young and middle-aged adults (N=190) |
Older adults (N=816) |
n (%) or M±SD |
n (%) or M±SD |
n (%) or M±SD |
Age (year) |
|
71.99±8.87 |
58.00±5.24 |
75.25±5.86 |
Gender |
Male |
289 (28.7) |
73 (38.4) |
216 (26.5) |
Female |
717 (71.3) |
117 (61.6) |
600 (73.5) |
Educational level |
≤Middle school |
743 (73.9) |
98 (51.6) |
645 (79.0) |
High school |
186 (18.5) |
61 (32.1) |
125 (15.3) |
≥Bachelors |
77 (7.7) |
31 (16.3) |
46 (5.6) |
Annual income of household (million won) |
|
27.03±31.73 |
43.29±52.40 |
23.25±23.00 |
1 quintile (bottom 20%) |
374 (37.2) |
33 (17.4) |
341 (41.8) |
2 quintile (20~40%) |
245 (24.4) |
31 (16.3) |
214 (26.2) |
3 quintile (40~60%) |
175 (17.4) |
44 (23.2) |
131 (16.1) |
4 quintile (60~80%) |
123 (12.2) |
46 (24.2) |
77 (9.4) |
5 quintile (above 80%) |
88 (8.8) |
36 (18.9) |
52 (6.4) |
Religion |
Seoul |
136 (13.5) |
29 (15.3) |
107 (13.1) |
Metropolitan city |
249 (24.8) |
49 (25.8) |
200 (24.5) |
Province |
621 (61.7) |
112 (58.9) |
509 (62.4) |
Occupational type |
Unemployed |
681 (67.7) |
75 (39.5) |
606 (74.3) |
Paid worker |
141 (14.0) |
73 (38.4) |
68 (8.3) |
Businessman, self-employed |
118 (11.7) |
29 (15.3) |
89 (10.9) |
Unpaid family worker |
66 (6.6) |
13 (6.8) |
53 (6.5) |
Smoking |
Never smoke |
704 (71.5) |
123 (66.1) |
581 (72.8) |
Former smoker/current nonsmoker |
182 (18.5) |
34 (18.3) |
148 (18.5) |
Current smoker |
98 (10.0) |
29 (15.6) |
69 (8.6) |
Drinking |
Non drinker |
590 (60.0) |
71 (38.2) |
519 (65.0) |
Moderate drinker |
293 (29.8) |
67 (36.0) |
226 (28.3) |
Heavy drinker |
101 (10.3) |
48 (25.8) |
53 (6.6) |
Moderate physical activity |
<3 times a week |
721 (73.3) |
119 (64.0) |
602 (75.4) |
≥3 times a week |
263 (26.7) |
67 (36.0) |
196 (24.6) |
Type of health insurance |
National health insurance |
911 (90.6) |
171 (90.0) |
740 (90.7) |
Medical care assistance |
95 (9.4) |
19 (10.0) |
76 (9.3) |
Number of chronic disease |
|
5.75±2.29 |
5.03±2.12 |
5.92±2.30 |
3~6 |
692 (68.8) |
153 (80.5) |
539 (66.1) |
7~9 |
242 (24.1) |
29 (15.3) |
213 (26.1) |
≥10 |
72 (7.2) |
8 (4.2) |
64 (7.8) |
Type of multimorbidity |
Not included musculoskeletal condition |
378 (37.6) |
98 (51.6) |
280 (34.3) |
Included musculoskeletal condition |
628 (62.4) |
92 (48.4) |
536 (65.7) |
Unmet healthcare needs |
Unmet healthcare needs |
217 (22.1) |
44 (23.7) |
173 (21.7) |
Not unmet healthcare needs |
767 (77.9) |
142 (76.3) |
625 (78.3) |
Table 3Health-related Quality of Life by General and Medical related Characteristics of Participants (N=1,006)†
Characteristics |
Young and middle-aged adults (N=190) |
Older adults (N=816) |
M±SD |
t or F (p) |
M±SD |
t or F (p) |
HRQOL |
|
0.87±0.12 |
|
0.84±0.12 |
3.30‡ (.001) |
Gender |
Male |
0.87±0.15 |
−0.27 (.791) |
0.88±0.09 |
6.99 (<.001) |
Female |
0.87±0.09 |
0.82±0.13 |
Educational level |
≤Middle schoola
|
0.87±0.11 |
4.21 (.016)
a, b<c |
0.83±0.12 |
11.75 (<.001)
a<b, c |
High schoolb
|
0.85±0.15 |
0.87±0.10 |
≥Bachelorsc
|
0.92±0.05 |
0.88±0.09 |
Annual income of household (million won) |
1 quintile (bottom 20%)a
|
0.80±0.14 |
4.59 (.001)
a<e |
0.82±0.13 |
2.97 (.019)
a<d |
2 quintile (20~40%)b
|
0.88±0.12 |
0.84±0.12 |
3 quintile (40~60%)c
|
0.88±0.08 |
0.85±0.12 |
4 quintile (60~80%)d
|
0.86±0.14 |
0.86±0.11 |
5 quintile (above 80%)e
|
0.92±0.05 |
0.86±0.11 |
Religion |
Seoul |
0.88±0.08 |
0.24 (.789) |
0.85±0.11 |
0.90 (.408) |
Metropolitan city |
0.87±0.11 |
0.83±0.13 |
Province |
0.87±0.13 |
0.84±0.12 |
Occupational type |
Unemployeda
|
0.84±0.16 |
2.20 (.090) |
0.82±0.13 |
10.98 (<.001)
a<b, c
b>d |
Paid workerb
|
0.89±0.08 |
0.89±0.07 |
Businessman, self-employedc
|
0.89±0.08 |
0.88±0.09 |
Unpaid family workerd
|
0.88±0.10 |
0.85±0.09 |
Smoking |
Never smokea
|
0.88±0.09 |
1.18 (.311) |
0.83±0.13 |
5.83 (.003)
a<b |
Former smoker/current nonsmokerb
|
0.85±0.18 |
0.86±0.10 |
Current smokerc
|
0.85±0.13 |
0.85±0.11 |
Drinking |
Non drinkera
|
0.85±0.14 |
2.59 (.078) |
0.82±0.13 |
16.45 (<.001)
a<b, c |
Moderate drinkerb
|
0.88±0.11 |
0.86±0.09 |
Heavy drinkerc
|
0.89±0.09 |
0.89±0.08 |
Moderate physical activity |
<3 times a week |
0.86±0.13 |
−2.17 (.031) |
0.83±0.13 |
−5.65 (<.001) |
≥3 times a week |
0.89±0.08 |
0.87±0.09 |
Type of health insurance |
National health insurance |
0.88±0.11 |
2.69 (.015) |
0.84±0.12 |
3.34 (.001) |
Medical care assistance |
0.77±0.16 |
0.79±0.11 |
Number of chronic disease |
3~6a
|
0.89±0.11 |
9.50 (<.001)
a>b>c |
0.85±0.10 |
30.45 (<.001)
a>b>c |
7~9b
|
0.82±0.14 |
0.82±0.12 |
≥10c
|
0.75±0.11 |
0.74±0.20 |
Type of multimorbidity |
Not included musculoskeletal condition |
0.86±0.14 |
−1.05 (.297) |
0.86±0.13 |
3.68 (<.001) |
Included musculoskeletal condition |
0.88±0.08 |
0.83±0.12 |
Unmet healthcare needs |
Unmet healthcare needs |
0.86±0.13 |
−0.90 (.369) |
0.79±0.13 |
−6.33 (<.001) |
Not unmet healthcare needs |
0.88±0.11 |
0.85±0.11 |
Table 4Factors influencing HRQOL of Participants (N=1,006)†
Variables |
Model 1 |
Model 2 |
Young and middle-aged adults (n=190) |
Older adults (n=816) |
B |
t |
p
|
B |
t |
p
|
Female (Male=0) |
0.01 |
0.42 |
.676 |
−0.02 |
−1.23 |
.220 |
Education (Below middle school=0) |
|
|
|
|
|
|
High school |
0.00 |
−0.14 |
.888 |
0.03 |
2.68 |
.008 |
≥Bachelors |
0.07 |
2.58 |
.011 |
0.03 |
1.53 |
.126 |
Annual income of household (million won) |
0.35 |
0.21 |
.831 |
−0.30 |
−0.16 |
.873 |
Occupational type (Paid worker=0) |
|
|
|
|
|
|
Unemployed |
0.00 |
−0.21 |
.830 |
−0.04 |
−2.72 |
.007 |
Businessman/self-employed |
0.01 |
0.48 |
.633 |
−0.01 |
−0.66 |
.507 |
Unpaid family worker |
−0.02 |
−0.45 |
.657 |
−0.02 |
−1.00 |
.320 |
Smoking (Never smoke=0) |
|
|
|
|
|
|
Former smoker/current nonsmoker |
−0.05 |
−1.66 |
.100 |
−0.01 |
−0.39 |
.694 |
Current smoker |
−0.07 |
−2.19 |
.030 |
−0.01 |
−0.69 |
.488 |
Drinking (Non drinker=0) |
|
|
|
|
|
|
Moderate drinker |
0.02 |
1.01 |
.314 |
0.03 |
3.07 |
.002 |
Heavy drinker |
0.05 |
2.04 |
.043 |
0.02 |
1.01 |
.315 |
Moderate physical activity (<3 times a week=0) |
|
|
|
|
|
|
More than 3 times a week |
0.02 |
0.91 |
.362 |
0.02 |
2.45 |
.015 |
Type of health insurance (NHI=0) |
|
|
|
|
|
|
Medical care assistance |
−0.04 |
−1.35 |
.180 |
−0.01 |
−0.71 |
.476 |
Number of chronic disease |
−0.01 |
−3.66 |
<.001 |
−0.01 |
−6.35 |
<.001 |
Type of multimorbidity (NMC=0) |
|
|
|
|
|
|
Included musculoskeletal condition |
0.01 |
0.56 |
.575 |
−0.03 |
−3.08 |
.002 |
Unmet healthcare needs (Yes=0) |
|
|
|
|
|
|
Not unmet healthcare needs |
0.01 |
0.31 |
.754 |
0.05 |
5.15 |
<.001 |
|
R2=.24, Adj. R2=.17, F=3.30, p<.001 R2=.19, Adj. R2=.17, F=11.33, p<.001 |