pISSN 1738-1495   eISSN 2384-0757
Open Access, Peer-reviewed
    Dement Neurocogn Disord. 2014 Dec;13(4):121-128. Korean.
    Published online Dec 31, 2014.
    https://doi.org/10.12779/dnd.2014.13.4.121
    © 2014 Korean Dementia Association
    Original Article

    Prevalence and Risk Factors of Dementia and MCI in Community-dwelling Elderly Koreans

    Il Mi Jang, M.D.,* Kyung-Bok Lee, M.D.,† Hakjae Roh, M.D.,† and Moo-Young Ahn, M.D.†,‡
      • *Department of Neurology, Daejeon Wellness Hospital, Daejeon, Korea.
      • †Department of Neurology, College of Medicine, Soonchunhyang University, Seoul, Korea.
      • ‡Yongsan-gu Regional Center for Dementia, Seoul, Korea.
    • Address for correspondence: Moo-Young Ahn, M.D. Department of Neurology, College of Medicine, Soonchunhyang University, 59 Daesagwan-ro, Yongsan-gu, Seoul 140-743, Korea. Tel: +82-2-709-9224, Fax: +82-2-709-9226, Email: neuron@schmc.ac.kr
    Received November 13, 2014; Revised December 08, 2014; Accepted December 08, 2014.

    This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

    Abstract

    Background

    We investigated the prevalence of dementia and mild cognitive impairment (MCI) and their risk factors in an urban community-dwelling elderly people over 65 years old.

    Methods

    A two-phase investigation was performed from January 2010 to December 2011. In Phase I, all subjects (n=9,485) responded to the Korean version of the Mini-Mental State Examination (K-MMSE). Based on the K-MMSE score the subjects were classified into two groups ('Normal' and 'Cognitive decline'). In Phase II, cognitive decline subjects were diagnosed as dementia or MCI according to the neuropsychological tests and doctor's interview. We also surveyed the socioeconomic and medical factors in Normal, Dementia and MCI groups. And we compared and analyzed the socioeconomic and medical risk factors by multiple logistic regressions in Dementia and MCI group.

    Results

    The prevalence of dementia and MCI was obtained 5.4% and 4.3%, respectively. Old age, alcohol intake, living together, low economic status, jobless in the past, diabetes mellitus, previous stroke, lower BMI and family history of dementia were associated with the increased dementia risk. Higher education, hypertension and physical activity were associated with the decreased dementia risk. And old age, alcohol intake, higher education, previous stroke, lower BMI and physical activity were common risk factors in MCI group.

    Conclusions

    The prevalence of dementia and MCI was obtained much lower than previous reports. Dementia and MCI patients had common socioeconomic and medical risk factors. It is also important to control the risk factors earlier to prevent the increase of patients in dementia. And in order to prove the hypothesis that early control of the risk factors can decrease the occurrence of dementia, the further prospective studies are needed.

    Keywords
    Prevalence; Risk Factors; Dementia; MCI

    Figures

    Fig. 1
    Summary of the study participants.

    Tables

    Table 1
    Socio-demographic and clinical characteristics of the subjects

    Table 2
    Socioeconomic factors associated with the risk of MCI and Dementia in a multiple logistic regression

    Table 3
    Medical factors associated with the risk of MCI and Dementia in a multiple logistic regression

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    MeSH Terms
    Aged*
    Dementia*
    Diabetes Mellitus
    Education
    Humans
    Hypertension
    Logistic Models
    Mild Cognitive Impairment
    Motor Activity
    Neuropsychological Tests
    Prevalence*
    Risk Factors*
    Stroke
    Metrics
    Share
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