A nomenclature for all signal recognition particle RNAs

  1. CHRISTIAN ZWIEB1,
  2. ROB W. VAN NUES2,
  3. MAGNUS ALM ROSENBLAD3,
  4. JEREMY D. BROWN2, and
  5. TORE SAMUELSSON3
  1. 1Department of Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, Texas 75710, USA
  2. 2Institute of Cell and Molecular Biosciences, The Medical School, University of Newcastle, Newcastle Upon Tyne NE2 4HH, UK
  3. 3Department of Medical Biochemistry, Goteborg University, SE-405 30 Goteborg, Sweden

Abstract

The signal recognition particle (SRP) is a cytosolic ribonucleoprotein complex that guides secretory proteins to biological membranes in all organisms. The SRP RNA is at the center of the structure and function of the SRP. The comparison of the growing number of SRP RNA sequences provides a rich source for gaining valuable insight into the composition, assembly, and phylogeny of the SRP. In order to assist in the continuation of these studies, we propose an SRP RNA nomenclature applicable to the three divisions of life.

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