Three New Diterpenoids from the Fruit of Vitex agnus-castus

Masateru Ono; Yumiko Nagasawa; Tsuyoshi Ikeda; Ryota Tsuchihashi; Masafumi Okawa; Junei Kinjo; Hitoshi Yoshimitsu; Toshihiro Nohara

doi:10.1248/cpb.57.1132

Notes

Three New Diterpenoids from the Fruit of Vitex agnus-castus

Masateru Ono, Yumiko Nagasawa, Tsuyoshi Ikeda, Ryota Tsuchihashi, Masafumi Okawa, Junei Kinjo, Hitoshi Yoshimitsu, Toshihiro Nohara

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Keywords: Vitex agnus-castus, Verbenaceae, chasteberry, diterpenoid, labdane, viteagnusin

JOURNAL FREE ACCESS

2009 Volume 57 Issue 10 Pages 1132-1135

DOI https://doi.org/10.1248/cpb.57.1132

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Abstract

Three new labdane-type diterpenoids, viteagnusins F, G, and H, were isolated from the hexane extract of fruit (chasteberry) of Vitex agnus-castus L. (Verbenaceae) along with seven known compounds including four labdane-type diterpenoids, one norlabdane-type diterpenoid, one aromadendrane-type sesquiterpenoid, and one flavonoid. The chemical structures of the three new labdane-type diterpenoids were determined on the basis of spectroscopic data as well as chemical evidence.

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