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Controversy in the Treatment of Gastric Cancer

  • Gastrointestinal Oncology
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

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References

  1. Boige V, Pignon J, Saint-Aubert B, et al. Final results of a randomized trial comparing preoperative 5-fluorouracil (F)/cisplatin (P) to surgery alone in adenocarcinoma of stomach and lower esophagus (ASLE): FNLCC ACCORD07-FFCD 9703 trial. 2007 ASCO Annual Meeting

  2. Cunningham D, Allum WH, Stenning SP, et al. Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. N Engl J Med 2006; 355:11–20

    Article  PubMed  CAS  Google Scholar 

  3. Sasako M, Yamaguchi T, Kinorshita T, et al. Randomized phase III trial comparing S-1 monotherapy versus surgery alone for stage II/III gastric cancer patients after curative D2 gastrectomy (ACTS-GC study). (Abstract No. 8). 2007 ASCO Gastrointestinal Cancers Symposium Orlando, FL: American Society of Clinical Oncology; 2007

  4. Roukos DH, Kappas AM. Perspectives in the treatment of gastric cancer. Nat Clin Pract Oncol 2005; 2: 98–107

    Article  PubMed  Google Scholar 

  5. Briasoulis E, Fatouros M, Roukos DH. Level I evidence in support of perioperative chemotherapy for operable gastric cancer: sufficient for wide clinical use?. Ann Surg Oncol 2007;14:2691–5

    Article  PubMed  Google Scholar 

  6. Roukos DH, Murray S, Briasoulis E. Molecular genetic tools shape a roadmap towards a more accurate prognostic prediction and personalized management of cancer. Cancer Biol Ther 2007;6:308–12

    PubMed  CAS  Google Scholar 

  7. Mansour JC, Tang L, Shah M, et al. Does graded histologic response after neoadjuvant chemotherapy predict survival for completely resected gastric cancer? Ann Surg Oncol 2007 Oct 2; [Epub ahead of print]

  8. Ajani JA. Can we understand the clinical biology of gastric cancer and exploit it? May be, but it is a challenge! Ann Surg Oncol 2007 Oct 12; [Epub ahead of print]

  9. Roukos DH. Early-stage gastric cancer: a highly treatable disease. Ann Surg Oncol 2004;11:127–9

    Article  PubMed  Google Scholar 

  10. Roukos DH, Lorenz M, Karakostas K, et al. Pathological serosa and node-based classification accurately predicts gastric cancer recurrence risk and outcome, and determines potential and limitation of a Japanese-style extensive surgery for Western patients: a prospective with quality control 10-year follow-up study. Br J Cancer 2001;84:1602–9

    Article  PubMed  CAS  Google Scholar 

  11. Sano T. Tailoring treatments for curable gastric cancer. Br J Surg 2007;94:263–4

    Article  PubMed  CAS  Google Scholar 

  12. Roukos DH, Hottenrott C, Encke A, et al. Primary gastric lymphomas: a clinicopathologic study with literature review. Surg Oncol 1994;3:115–25

    Article  PubMed  CAS  Google Scholar 

  13. Kappas AM, Fatouros M, Roukos DH. Is it time to change surgical strategy for gastric cancer in the United States?. Ann Surg Oncol 2004; 11: 727–30.

    Article  PubMed  Google Scholar 

  14. Wu CW, Hsiung SA, Lo SS, et al. Nodal dissection for patients with gastric cancer: a randomised trial. Lancet Oncol 2006;7:309–15

    Article  PubMed  CAS  Google Scholar 

  15. Macdonald JS, Smalley SR, Benedetti J, et al. Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction. N Engl J Med 2001; 345: 725–30

    Article  PubMed  CAS  Google Scholar 

  16. Roukos DH. Adjuvant chemoradiotherapy in gastric cancer: wave goodbye to extensive surgery? Ann Surg Oncol 2002; 9: 220–1

    Article  PubMed  Google Scholar 

  17. Roukos DH, Kappas AM. Targeting the optimal extent of lymph node dissection for gastric cancer. J Surg Oncol 2002; 8: 59–62

    Article  Google Scholar 

  18. Siewert JR, Bottcher K, Stein HJ, et al. Relevant prognostic factors in gastric cancer: ten-year results of the German Gastric Cancer Study. Ann Surg 1998; 228: 449–61

    Article  PubMed  CAS  Google Scholar 

  19. Roukos DH. Extended lymphadenectomy in gastric cancer: when, for whom and why. Ann R Coll Surg Engl 1998; 80: 16–24

    PubMed  CAS  Google Scholar 

  20. Roukos DH. Extended (D2) lymph node dissection for gastric cancer: do patients benefit?. Ann Surg Oncol 2000; 7: 253–5

    Article  PubMed  CAS  Google Scholar 

  21. Roukos DH, Briasoulis E. Individualized preventive and therapeutic management of hereditary breast ovarian cancer. Nat Clin Pract Oncol 2007; 4:578–90

    Article  PubMed  CAS  Google Scholar 

  22. Roukos DH. Innovative genomic-based model for personalized treatment of gastric cancer integrating current standards and new technologies. Expert Rev Mol Diagn 2008; 8:29–39

    Article  PubMed  CAS  Google Scholar 

  23. Norton JA, Ham CM, Van Dam J, et al. CDH1 truncating mutations in the E-cadherin gene: an indication for total gastrectomy to treat hereditary diffuse gastric cancer. Ann Surg 2007;245:873–9

    Article  PubMed  Google Scholar 

  24. Chung DC, Yoon SS, Lauwers GY, et al. Case records of the Massachusetts General Hospital. Case 22–2007. A woman with a family history of gastric and breast cancer. N Engl J Med 2007;357:283–91

    Article  PubMed  CAS  Google Scholar 

  25. Roukos DH, Kappas AM, Tsianos E. Role of surgery in the prophylaxis of hereditary cancer syndromes. Ann Surg Oncol 2002; 9: 607–9

    PubMed  Google Scholar 

  26. Roukos DH, Agnanti NJ, Paraskevaidis E, et al. Approaching the dilemma between prophylactic bilateral mastectomy or oophorectomy for breast and ovarian cancer prevention in carriers of BRCA1 or BRCA2 mutations. Ann Surg Oncol 2002; 9: 941–3

    PubMed  Google Scholar 

  27. Fatouros M, Baltoyiannis G, Roukos DH. The predominant role of surgery in the prevention and new trends in the surgical treatment of women with BRCA1/2 mutations. Ann Surg Oncol 2007 Oct 17; [Epub ahead of print]; DOI: 10.1245/s10434-007-9612-4

  28. Agnantis NJ, Paraskevaidis E, Roukos D. Preventing breast, ovarian cancer in BRCA carriers: rational of prophylactic surgery and promises of surveillance. Ann Surg Oncol 2004;11:1030–4

    Article  PubMed  Google Scholar 

  29. Roukos DH, Kappas AM, Agnantis NJ. Perspectives and risks of breast-conservation therapy for breast cancer. Ann Surg Oncol 2003; 10: 718–21

    Article  PubMed  Google Scholar 

  30. Fatouros M, Roukos DH, Arampatzis I, et al. Factors increasing local recurrence in breast-conserving surgery. Expert Rev Anticancer Ther 2005; 5: 737–45

    Article  PubMed  Google Scholar 

  31. Roukos DH. Prognosis of breast cancer in carriers of BRCA1 and BRCA2 mutations. N Engl J Med 2007; 357: 1555–6; author reply 1556

    Google Scholar 

  32. Briasoulis E, Liakakos T, Dova L, et al. Selecting a specific pre- or postoperative adjuvant therapy for individual patients with operable gastric cancer. Expert Rev Anticancer Ther 2006;6:931–9

    Article  PubMed  Google Scholar 

  33. Liakakos T, Roukos DH. More controversy than ever: challenges and promises towards personalized treatment of gastric cancer: Ann Surg Oncol 2008; DOI: 10.1245/s10434-007-9798-5

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Authors and Affiliations

  1. School of Medicine, Department of Surgery, University of Ioannina, Ioannina, Greece

    Michael Fatouros MD & Dimosthenis Ziogas MD

Authors
  1. Michael Fatouros MD
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  2. Dimosthenis Ziogas MD
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Correspondence to Dimosthenis Ziogas MD.

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Fatouros, M., Ziogas, D. Controversy in the Treatment of Gastric Cancer. Ann Surg Oncol 15, 1795–1797 (2008). https://doi.org/10.1245/s10434-007-9764-2

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  • DOI: https://doi.org/10.1245/s10434-007-9764-2

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