Open Access
September, 1983 Asymptotic Distribution Theory for Cox-Type Regression Models with General Relative Risk Form
Ross L. Prentice, Steven G. Self
Ann. Statist. 11(3): 804-813 (September, 1983). DOI: 10.1214/aos/1176346247

Abstract

The theory and application of the Cox (1972) failure time regression model has, almost without exception, assumed an exponential form for the dependence of the hazard function on regression variables. Other regression forms may be more natural or descriptive in some applications. For example, a linear relative risk regression model provides a convenient framework for studying epidemiologic risk factor interactions. This note uses the counting process formulation of Andersen and Gill (1982) to develop asymptotic distribution theory for a class of intensity function regression models in which the usual exponential regression form is relaxed to an arbitrary non-negative twice differentiable form. Some stability and regularity conditions, beyond those of Andersen and Gill, are required to show the consistency of the observed information matrix, which in general need not be positive semidefinite.

Citation

Download Citation

Ross L. Prentice. Steven G. Self. "Asymptotic Distribution Theory for Cox-Type Regression Models with General Relative Risk Form." Ann. Statist. 11 (3) 804 - 813, September, 1983. https://doi.org/10.1214/aos/1176346247

Information

Published: September, 1983
First available in Project Euclid: 12 April 2007

zbMATH: 0526.62017
MathSciNet: MR707931
Digital Object Identifier: 10.1214/aos/1176346247

Subjects:
Primary: 62E20
Secondary: 60G15 , 62G05

Keywords: Censoring , counting process , Cox-regression , failure-time data , intensity process , martingale , partial likelihood , time-dependent covariates

Rights: Copyright © 1983 Institute of Mathematical Statistics

Vol.11 • No. 3 • September, 1983
Back to Top