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The effect of spray-drying feed temperature and subsequent crystallization conditions on the physical form of lactose

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References

  1. Sebhatu T, Angberg M, Ahlneck C. Assessment of the degree of disorder in crystalline solids by isothermal microcalorimetry. Int J Pharm. 1993;104:135–144.

    Article  Google Scholar 

  2. Chidavaenzi OC, Buckton G, Koosha F, Pathak R. The use of thermal techniques to assess the impact of feed concentration on the amorphous content and polymorphic forms present in spray dried lactose. Int J Pharm. 1997;159:67–74.

    Article  CAS  Google Scholar 

  3. Briggner L-E, Buckton G, Bystrom K, Darcy P. The use of isothermal microcalorimetry in the study of changes in crystallinity induced during the processing of powders. Int J Pharm. 1994;105:125–135.

    Article  CAS  Google Scholar 

  4. Dwivedi SK, Mitchell AG. Gas chromatographic analysis of anomeric composition of lactose. J Pharm Sci. 1989;78(12):1055–1056.

    Article  PubMed  CAS  Google Scholar 

  5. Angberg M, Nystrom C, Castensson S. Evaluation of heat-conduction microcalorimetry in pharmaceutical stability studies, III: crystallographic changes due to water vapour uptake in anhydrous lactose powder. Int J Pharm. 1991;73:209–220.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Pharmaceutics, School of Pharmacy, University of London, 29-39 Brunswick Square, WC1N 1AX, London

    Graham Buckton & Owen C. Chidavaenzi

  2. SmithKline Beecham Pharmaceuticals, New Frontiers Science Park (South), Third Avenue, CM 19 5AW, Harlow, Essex, UK

    Fariba Koosha

Authors
  1. Graham Buckton
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  2. Owen C. Chidavaenzi
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  3. Fariba Koosha
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Correspondence to Graham Buckton.

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Buckton, G., Chidavaenzi, O.C. & Koosha, F. The effect of spray-drying feed temperature and subsequent crystallization conditions on the physical form of lactose. AAPS PharmSciTech 3, Technical Note 1 (2002). https://doi.org/10.1208/pt0304

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  • DOI: https://doi.org/10.1208/pt0304

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