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Levy G, Hayes B, “Physiochemical Basis of the Buffered Acetylsalicylic Acid Controversy New Engl. J. Med. 262:1053–1058 (1960)”—The Backstory

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  • Theme: Landmark Publications in the Pharmaceutical Sciences—The Backstory
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References

  1. Levy G. Effect of certain tablet formulation factors on dissolution rate of the active ingredient. I. Importance of using appropriate agitation intensities for in vitro dissolution rate measurements to reflect in vivo conditions. J Pharm Sci. 1963;52:1039–46.

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  2. Levy G, Leonards JR, Procknal JA. Development of in vitro dissolution tests which correlate quantitatively with dissolution rate-limited drug absorption in man. J Pharm Sci. 1965;54:1719–22.

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  3. Levy G. Comparison of dissolution and absorption rates of different commercial aspirin tablets. J Pharm Sci. 1961;50:388–92.

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  4. Levy G, Hayes BA. Physicochemical basis of the buffered acetylsalicylic acid controversy. New Engl J Med. 1960;262:1053–8.

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Authors and Affiliations

  1. The State University of New York at Buffalo, Buffalo, New York, USA

    Gerhard Levy

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  1. Gerhard Levy
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Correspondence to Gerhard Levy.

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Guest Editor: Ho-Leung Fung

Dr. Levy is retired and can be reached through email.

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Levy, G. Levy G, Hayes B, “Physiochemical Basis of the Buffered Acetylsalicylic Acid Controversy New Engl. J. Med. 262:1053–1058 (1960)”—The Backstory. AAPS J 13, 320–322 (2011). https://doi.org/10.1208/s12248-011-9280-y

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  • DOI: https://doi.org/10.1208/s12248-011-9280-y

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