Abstract
Pectus excavatum (PE) is the most common chest wall deformity occurring with an incidence of one in 300—400 live births. In the operations of chest deformities, there is a debate among methods of surgery and the optimal age of these operations until the mid-1990s. So we've decided to investigate the probable effects of type and number of costal cartilage resections, which were carried out before bone growth maturation on the thoracic wall development.
Forty male, 6 weeks of age rabbits were evaluated in four groups. Rabbits in group 1 underwent partial costochondral resection of the two ribs (right 3 and 4); rabbits in group 2 underwent total resection of those. Those in group 3 underwent partial costochondral resection of four ribs (right 3- 6) and rabbits in group 4 underwent total resection of those. Pathological analyses were evaluated at the twenty-fourth week.
There were statistically significant differences for number of lymphocyte, fibroblast and osteoblasts among groups (p < 0.05).
In conclusion, costal cartilage resection is not an innocent procedure. Usage of minimally invasive surgery for elementary repair of the chest deformities have been reported by many centers in all around the world. This study has revealed that the thoracic wall development was affected by the cellular level, such as the morphological development between the groups. This effect is more prominent in the setting of unsaved growth centers of the ribs and/or at least four cartilages resection.
- Copyright ©ERS 2015