Cells and Nanomaterial-Based Tissue Engineering Techniques in the Treatment of Bone and Cartilage Injuries
Over the last decade the interest in the technology of tissue engineering (TE) has grown enormously, especially with respect to reparative techniques. New methods and therapeutic tools have been designed; various cell types used and novel drugs and growth factors applied for the repair
of lesions in numerous tissues, in particular bone and cartilage, resulting from injuries or degenerative changes due to aging of the population. The TE requires the application of various methods, including sophisticated surgical procedures supported by techniques of cell biology and biotechnology.
The latter techniques are required for choosing appropriate cell types for transplantation, elaborating optimal cell culture conditions, designing scaffolds for cell delivery, affixing temporary implantable devices in the lesion site and supplying drugs and growth factors. In the present review
we describe and discuss various TE techniques used in bone and cartilage repair including: recently applied principal cell sources, and the application of nanotube-based scaffolds in the regeneration of joint cartilage.
Keywords: Bone and Cartilage Injuries Repair; Carbon Nanotubes; Tissue Engineering
Document Type: Research Article
Affiliations: 1: Department of Orthopedics and Traumatology, Poznan University of Medical Sciences, 135-147, 28 Czerwca 1956 St, 61-545 Poznan, Poland 2: Faculty of Chemistry, Adam Mickiewicz University, 61-614 Poznan, Poland 3: Centre for Stem Cell Research (CSCR), A Unit of Institute for Stem Cell Biology and Regenerative Medicine-Bengaluru, Christian Medical College Campus, Vellore 632002, India
Publication date: 01 September 2016
- Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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