Korean J Phys Anthropol. 2018 Mar;31(1):27-34. Korean.
Published online Mar 30, 2018.
© 2018 Korean Association of Physical Anthropologists
Original Article

Paleopathological Studies of Infectious Disease: Examination of the Osteoarchaeological Research

Eun Jin Woo,1 Jae-Hyun Kim,2 Chae Lin Jeon,3 and Sunyoung Pak3
    • 1Department of History, College of Liberal Art, Sejong University, Korea.
    • 2Department of Archaeology and Art History, College of Humanities, Dong-A University, Korea.
    • 3Department of Anthropology, College of Social Sciences, Seoul National University, Korea.
Received January 16, 2018; Revised March 19, 2018; Accepted March 20, 2018.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Reconstructing the impact of infectious disease on past populations is one of the main fields in paleopathological studies. The initial phase of paleopathology was descriptive, focusing on the identification and presence of disease in the past. However, currently paleopathological studies are moving toward probing questions about the larger picture of origin and transmission of disease agents. In this study, paleopathological studies of major infectious disease (i.e., tubuerculosis, treponemal disease and leprosy) were reviewed through osteoarcheological work published in American Journal of Physical Anthropology, International Journal of Osteoarchaeology, Journal of Archaeological Science and International Journal of Paleopathology from 1981 to 2017.

A basic objective of this research was to examine many types of research in paleopathology and to characterize research trend in this field. As paleopathological studies becomes more abundant, the approaches to infectious disease have been increasingly specialized and interdisciplinary from 1980. Also, methodology used in paleopathology continues to evolve through the holistic approaches of molecular analysis, radiology and histopathology. Ultimately, this study reinforces the importance for retention of large-scale skeletal collections for paleopathological study in population perspective. In the near future, Korean paleopathology can contribute in the reconstructions of the history of disease and its effect on past human populations.

Keywords
Infectious disease; Paleopathology; Human skeleton; Tuberculosis; Syphilis; Leprosy

Figures

Fig. 1
Article categories published in AJPA and IJOA by period.

Tables

Table 2
Classification of articles examined in this study

Table 3
Articles from major anthropological journals split by article categories

Table 4
Methodology used in the articles by journal and period

Table 5
Methodology of the articles split by infectious disease

References

    1. Inhorn MC, Brown PJ. The anthropology of infectious disease. Annu Rev Anthropol 1990;19:89–117.
    1. Ortner DJ. Differential diagnosis of skeletal lesions in infectious disease. In: Pinhasi R, Mays S, editors. Advances in human palaeopathology. Chichester, England: John Wiley & Sons, Ltd; 2008. pp. 189-214.
    1. Molnar E, Palfi G. Probable cases of skeletal infections in the 17th century anthropological series from Bácsalmás (Hungary). Acta Biol Szeged 1994;40:117–133.
    1. Armelagos GJ, Brown PJ, Turner B. Evolutionary, historical and political economic perspectives on health and disease. Soc Sci Med 2005;61:755–765.
    1. Harper KN, Zuckerman MK, Harper ML, Kingston JD, Armelagos GJ. The origin and antiquity of syphilis revisited: an appraisal of Old World pre-Columbian evidence for treponemal infection. Am J Phys Anthropol 2011;146 Suppl 53:S99–133.
    1. Zuckerman MK, Harper KN. Paleoepidemiological and biocultural approaches to ancient disease: the origin and antiquity of syphilis. In: Zuckerman MK, Martin DL, editors. New directions in biocultural anthropology. New Jersey: John Wiley & Sons; 2016. pp. 317-335.
    1. Monot M, Honore N, Garnier T, Araoz R, Coppee JY, Lacroix C, et al. On the origin of leprosy. Science 2005;308:1040–1042.
    1. Stone AC, Wilbur AK, Buikstra JE, Roberts CA. Tuberculosis and leprosy in perspective. Am J Phys Anthropol 2009;140 Suppl 49:S66–S94.
    1. Suzuki T, Fujita H, Choi JG. New evidence of tuberculosis from prehistoric Korea-Population movement and early evidence of tuberculosis in Far East Asia. Am J Phys Anthropol 2008;136:357–360.
    1. Mays S. A perspective on human osteoarchaeology in Britain. Int J Osteoarchaeol 1997;7:600–604.
    1. Mays S. Human osteoarchaeology in the UK 2001-2007: a bibliometric perspective. Int J Osteoarchaeol 2000;20:192–204.
    1. Ortner DJ, Putschar W. In: Identification of pathological conditions in human skeletal remains. Washington: Smithsonian Institution Press; 1985. pp. 130.
    1. Spigelman M, Lemma E. The use of the polymerase chain reaction (PCR) to detect mycobacterium tuberculosis in ancient skeletons. Int J Osteoarchaeol 1993;3:137–143.
    1. Braun M, Pfeiffer S. DNA from mycobacterium tuberculosis complex identified in North American, Pre-Columbian human skeletal remains. J Archaeol Sci 1998;25:271–277.
    1. Comas I, Coscolla M, Luo T, Borrell S, Holt KE, Kato-Maeda M, et al. Out-of-Africa migration and Neolithic coexpansion of mycobacterium tuberculosis with modern humans. Nat Genet 2013;45:1176–1182.
    1. Ortner DJ. Paleopathology: implications for the history and evolution of tuberculosis. In: Pálfi G, Dutour O, Deák J, Hutás IS, editors. Tuberculosis: past and present. Hungary: Golden Book Publisher Ltd; 1999. pp. 255-261.
    1. Morse D. Pre-historic tuberculosis in America. Am Rev Respir Dis 1961;83:489–504.
    1. Morse D. On tuberculosis. In: Brothwell D, Sandison AT, editors. Diseases in antiquity. Springfield: Charles C. Thomas; 1967. pp. 249-271.
    1. Ritchie WA. Paleopathological evidence suggesting pre-Columbian tuberculosis in New York State. Am J Phys Anthropol 1952;10:305–311.
    1. Lichtor J, Lichtor A. Paleopathological evidence suggesting pre-Columbian tuberculosis of the spine. J Bone Joint Surg 1957;39:1398–1399.
    1. Holloway KL, Henneberg R, de Barros Lopes M, Henneberg M. Evolution of human tuberculosis: a systematic review and meta-analysis of paleopathological evidence. HOMO-J Comp Hum Bio 2011;62:402–458.
    1. Salo WL, Aufderheide AC, Buikstra J, Holcomb TA. Identification of mycobacterium tuberculosis DNA in a pre-Columbian Peruvian mummy. Proceedings of the National Academy of Sciences 1994;91:2091–2094.
    1. Arriaza BT, Salo WL, Aufderheide AC, Holcomb TA. Pre-Columbian tuberculosis in Northern Chile: molecular and skeletal evidence. Am J Phys Anthropol 1995;98:37–45.
    1. Bos KI, Harkins KM, Herbig A, Coscolla M, Weber N, Comas I, et al. Pre-Columbian mycobacterial genomes reveal seals as a source of New World human tuberculosis. Nature 2014;514:494–497.
    1. Suzuki T. Paleopathological study on infectious disease in Japan. In: Ortner DJ, Aufderheide AC, editors. Human paleopathology: current syntheses and future options. Washington DC: Smithsonian Institution Press; 1991. pp. 128-139.
    1. Pechenkina EA, Benfer RA Jr, Ma X. Diet and health in the Neolithic of the Wei and Middle Yellow River Basins, Northern China. In: Cohen MN, Crane-Kramer GNM, editors. Ancient health: skeletal indicators of agricultural and economic intensification. Gainesville: University of Florida Press; 2007. pp. 255-272.
    1. Suzuki T, Inoue T. Earliest evidence of spinal tuberculosis from the aneolithic Yayoi period in Japan. Int J Osteoarchaeol 2007;17:392–402.
    1. Blau S, Yagodin V. Osteoarchaeological evidence for leprosy from Western Central Asia. Am J Phys Anthropol 2005;126:150–158.
    1. Tayles N, Buckley HR. Leprosy and tuberculosis in Iron Age southeast Asia? Am J Phys Anthropol 2004;125:239–256.
    1. Robbins G, Tripathy VM, Misra VN, Mohanty RK, Shinde VS, Gray KM, et al. Ancient skeletal evidence for leprosy in India (2000 BC). PLoS One 2009;4:e5669
    1. Taylor GM, Blau S, Mays S, Monot M, Lee OYC, Minnikin DE, et al. Mycobacterium leprae genotype amplified from an archaeological case of lepromatous leprosy in Central Asia. J Archaeol Sci 2009;36:2408–2414.
    1. Suzuki K, Takigawa W, Tanigawa K, Nakamura K, Ishido Y, Kawashima A, et al. Detection of Mycobacterium leprae DNA from archaeological skeletal remains in Japan using whole genome amplification and polymerase chain reaction. PLoS One 2010;5:e12422
    1. Barnes I, Thomas MG. Evaluating bacterial pathogen DNA preservation in museum osteological collections. Proceedings of the Royal Society of London B: Biological Science 2006;273:645–653.
    1. Bouwman AS, Brown TA. The limits of biomolecular palaeopathology: ancient DNA cannot be used to study venereal syphilis. J Archaeol Sci 2005;32:703–713.
    1. Kolman CJ, Centurion-Lara A, Lukehart SA, Owsley DW, Tuross N. Identification of Treponema pallidum subspecies pallidum in a 200-year-old skeletal specimen. J Infect Dis 1999;180:2060–2063.
    1. Mark L, Gulyas-Fekete G, Marcsik A, Molnar E, Palfi G. Analysis of ancient mycolic acids by using MALDI TOF MS: response to “Essentials in the use of mycolic acid biomarkers for tuberculosis detection” by Minnikin et al., 2010. J Archaeol Sci 2011;38:1111–1118.
    1. Roberts CA, Millard AR, Nowell GM, Gröcke DR, Macpherson CG, Pearson DG, et al. Isotopic tracing of the impact of mobility on infectious disease: the origin of people with treponematosis buried in Hull, England, in the late medieval period. Am J Phys Anthropol 2013;150:273–285.
    1. Guichón RA, Buikstra JE, Stone AC, Harkins KM, Suby JA, Massone M, et al. Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence. Int J Paleopathol 2015;11:92–101.
    1. Crespo FA, Klaes CK, Switala AE, DeWitte SN. Do leprosy and tuberculosis generate a systemic inflammatory shift? Setting the ground for a new dialogue between experimental immunology and bioarchaeology. Am J Phys Anthropol 2017;162:143–156.

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