Abstract:
A new instrument has been constructed whose purpose is to study time-resolved photodissociation (TRPD) of small peptide ions. Laser desorption of neutral peptides is combined with laser photoionization in an ion trap followed by thermalization, laser photodissociation and time of flight mass analysis. Ionization and excitation take place through an aromatic chromophore at the C-terminus of the peptide whereas dissociation produces the immonium ion at the N-terminus. The long-range purpose is to uncover the role of IVR in unimolecular fragmentations of peptide radical cations. One avenue is the determination of microcanonical rate constants at a well-defined internal energy E for a series of peptides possessing the same chromophore, undergoing the same fragmentation but having a variable number of degrees of freedom. This paper demonstrates the feasibility of the method and provides the first attempts at rate measurements for the peptide leucyl tyrosine (LeuTyr).
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received 6 January 2002 Published online 13 September 2002
Rights and permissions
About this article
Cite this article
Cui, W., Hu, Y. & Lifshitz, C. Time resolved photodissociation of small peptide ions . Eur. Phys. J. D 20, 565–571 (2002). https://doi.org/10.1140/epjd/e2002-00139-6
Issue Date:
DOI: https://doi.org/10.1140/epjd/e2002-00139-6