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Canavan’s disease
  1. J M S Pearce
  1. 304 Beverley Road, Analby, Hull HU10 7BG, UK; jmspearce@freenet.co.uk

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    Myrtelle May Canavan (1879–1953) described a progressive familial spongy degeneration of the cerebral white matter.1 Since van Bogaert and Bertrand2,3 also described the condition, and established its nosology, it is known as Canavan’s disease or, van Bogaert–Bertrand2,4 syndrome.

    Myrtelle Canavan was an American neuropathologist, born 24 June 1879 in St Johns, Michigan.5 She graduated MD, at the Michigan State College, and the Women’s Medical College of Pennsylvania in 1905. She married Dr James Francis Canavan. In 1907, while working as laboratory …

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