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Study of the 3D Structure of a Hydrogel with Gold Nanoparticles by Cryogenic Electron Microscopy

  • POLYMER, BIOORGANIC, AND HYBRID NANOMATERIALS
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Abstract

A hydrogel with gold nanoparticles stabilized in a citrate buffer is obtained by dehydration from a solution (sol-gel transition). The morphological characteristics of the hydrogel are studied using cryogenic transmission electron microscopy, in particular cryoelectron tomography. The spatial structure of the hydrogel is studied in three dimensions. The dimensional parameters of the nanoparticles and distances to nearest neighbors are determined. It is found that most of the nanoparticles are in a bound state and form clusters in the process of hydrogel formation.

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Authors and Affiliations

  1. National Research Center Kurchatov Institute, Moscow, Russia

    A. A. Mikhutkin, R. A. Kamyshinsky, N. M. Kuznetsov & A. L. Vasiliev

  2. Shubnikov Institute of Crystallography, Federal Research Center Crystallography and Photonics, Russian Academy of Sciences, Moscow, Russia

    R. A. Kamyshinsky, P. V. Lebedev-Stepanov, A. S. Stepko & A. L. Vasiliev

  3. National Research Nuclear University MEPhI, Moscow, Russia

    P. V. Lebedev-Stepanov

Authors
  1. A. A. Mikhutkin
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  2. R. A. Kamyshinsky
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  3. N. M. Kuznetsov
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  4. P. V. Lebedev-Stepanov
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  5. A. S. Stepko
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  6. A. L. Vasiliev
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Corresponding authors

Correspondence to A. A. Mikhutkin or A. L. Vasiliev.

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Mikhutkin, A.A., Kamyshinsky, R.A., Kuznetsov, N.M. et al. Study of the 3D Structure of a Hydrogel with Gold Nanoparticles by Cryogenic Electron Microscopy. Nanotechnol Russia 17, 396–401 (2022). https://doi.org/10.1134/S2635167622030119

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  • DOI: https://doi.org/10.1134/S2635167622030119

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