Abstract
The distribution of the atypical protein kinase Cζ in the nervous system of the adult and juvenile terrestrial snail Helix aspersa L. was studied immunocytochemically. Immunoreactive (IR) elements were detected in all CNS ganglia. The pattern of immunoreactivity included cytoplasmic staining of many CNS neurons, fibers in the CNS tracts and nerves, and ultrathin fibers and single varicosities inside the ganglia neuropil, which is the location of the major zones of synaptic contacts. The primary neurites and their proximal branches were not immunoreactive. The relatively low immunoreactivity of the fibers did not correspond to the presence of numerous Cζ-IR cell bodies. In the juvenile CNS, the IR neuropil was better developed than in the adult CNS, while immunoreactivity was practically absent in the cell bodies. We conclude that the atypical protein kinase Cζ is present in the snail CNS, while in the CNS neuropil it is predominantly located in varicosities.
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Original Russian Text © V.N. Ierusalimsky, A.A. Borodinova, P.M. Balaban, 2015, published in Neirokhimiya, 2015, Vol. 32, No. 4, pp. 295–301.
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Ierusalimsky, V.N., Borodinova, A.A. & Balaban, P.M. Localization of the atypical protein kinase Cζ in the Nervous System of the terrestrial snail Helix . Neurochem. J. 9, 254–259 (2015). https://doi.org/10.1134/S1819712415040091
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DOI: https://doi.org/10.1134/S1819712415040091