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Simultaneous detection of epinephrine, uric acid, and ascorbic acid with graphene-modified electrode

  • Applied Electrochemistry and Metal Protection from Corrosion
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Abstract

A graphene-modified glassy carbon electrode was obtained via drop-casting method and applied to the simultaneous detection of epinephrine, uric acid, and ascorbic acid by cyclic voltammetry in a phosphate buffer solution (pH 3.0). The oxidation potentials of epinephrine, uric acid, and ascorbic acid were 0.484, 0.650, and 0.184 V at the graphene-modified glassy carbon electrode, respectively. The peak separation between epinephrine Pand uric acid, epinephrine and ascorbic acid, and uric acid and ascorbic acid was about 166, 300, and 466 mV, respectively. So, this graphene-modified electrode can be used for simultaneous determination of each component in a mixture.

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References

  1. Wang, S.f., Du, D., and Zou, Q.C., Talanta, 2002, vol. 57, no. 4, pp. 687–692.

    Article  CAS  Google Scholar 

  2. Atta, N. F., Galal, A., and El-Ads, E.H., Analyst, 2012, vol. 137, no. 11, pp. 2658–2668.

    Article  CAS  Google Scholar 

  3. Luczak, T., Electrochim. Acta, 2009, vol. 54, no. 245, pp. 5863–5870.

    Article  CAS  Google Scholar 

  4. Shahrokhiana, S., Ghalkhania, M., and Amini, M.K., Sens. Actuators, B, 2009, vol. 137, no. 2, pp. 669–675.

    Article  Google Scholar 

  5. Bouhouti, H.E., Rodríguez, I.N. Cisnerosa, J.L.H.H., de El Kaoutita, M., Temsamanib, K.R., Bouchtab, D., and Aguilera, L.M.C., Talanta, 2009, vol. 79, no. 1, pp. 22–26.

    Article  Google Scholar 

  6. Shahrokhian, S. and Khafaji, M., Electrochim. Acta, 2010, vol. 55, no. 28, pp. 9090–9096

    Article  CAS  Google Scholar 

  7. Shahrokhian, S. and Saberi, R.S., Electrochim. Acta, 2011, vol. 57, pp. 132–138.

    Article  CAS  Google Scholar 

  8. Pihel, K., Schroeder, T.J., and Wightman, R.M., Anal. Chem., 1994, vol. 66, pp. 4532–4537.

    Article  CAS  Google Scholar 

  9. Deftereos, T.N., Calokerinos, A.C., and Efstathiou, C.E., Analyst, 1993, vol. 118, no. 6, pp. 627–632.

    Article  CAS  Google Scholar 

  10. Lu, X.Q., Li, Y.Y., Du, J., Zhou, X.B., Xue, Z.H., Liu, X.H., and Wand A.Z., Electrochim. Acta, 2011, vol. 56, no. 21, pp. 7261–7266.

    Article  CAS  Google Scholar 

  11. Liberopoulos, E.N., Miltiodous, G.A., and Elisaf, M.S., Lancet, 2004, vol. 364, no. 9430, pp. 246–247

    Article  Google Scholar 

  12. Zhang, L., Wang, Z.N., Xia, Y., Kai, G.Y., Chen, W.S., and Tang, K.X., Crit. Rev. Biotechno, 2007, vol. 27, no. 3, pp. 173–182.

    Article  CAS  Google Scholar 

  13. Ren, W., Luo, H.Q., and Li, N.B., Biosen. Bioelectron, 2006, vol. 21, no. 7, pp. 1086–1092.

    Article  CAS  Google Scholar 

  14. Ensafi, A.A., Rezaei, B., Mirahmadi, Zare, S.Z., and Taei, M., Sensor Actuat. B-Chem., 2010, vol. 150, no. 1, pp. 321–329.

    Article  CAS  Google Scholar 

  15. Zhang, Y., Ren, W., and Zhang, S.L., Int. J. Electrochem. Sci., 2013, vol. 8, pp. 6839–6850.

    CAS  Google Scholar 

  16. Novoselov, K.S., Geim, A.K., Morozov, S.V., Jiang, D., Zhang, Y., Dubonos, S.V., Grigorieva, I.V., and Firsov, A.A., Science, 2004, vol. 306, no. 5696, pp. 666–669.

    Article  CAS  Google Scholar 

  17. Gilje, S., Han, S., Wang, M., Wang, K.L., and Kaner, R.B., Nano Lett., 2007, vol. 7, no. 11, pp. 3394–3398.

    Article  CAS  Google Scholar 

  18. Bunch, J.S., van der Zande, A.M., Verbridge, S.S., Frank, I.W., Tanenbaum, D., Parpia, J.M., Craighead, H.G., and McEuen, P.L., Science, 2007, vol. 315, pp. 490–493.

    Article  CAS  Google Scholar 

  19. Li, D. and Kaner, R.B., Science, 2008, vol. 320, no. 5880, pp. 1170–1171.

    Article  CAS  Google Scholar 

  20. Ameen, S., Akhtar, M.S., and Shin, H.S., Sensor Actuat. B-Chem, 2012, vol. 173, pp. 177–183.

    Article  CAS  Google Scholar 

  21. Tian, J., Zhao, H., Zhao, H., and Quan, X., Microchim Acta, 2012, vol. 179, nos. 1–2, pp. 163–170.

    Article  CAS  Google Scholar 

  22. Chen, M.F., Ma, X.Y., and Li, X., J. Solid State Chem., 2012, vol. 16, no.10, pp. 3261–3266.

    CAS  Google Scholar 

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Correspondence to X. Y. Ma.

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Original Russian Text © M.F. Chen, X.Y. Ma, 2014, published in Zhurnal Prikladnoi Khimii, 2014, Vol. 87, No. 2, pp. 221–226.

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Chen, M.F., Ma, X.Y. Simultaneous detection of epinephrine, uric acid, and ascorbic acid with graphene-modified electrode. Russ J Appl Chem 87, 200–206 (2014). https://doi.org/10.1134/S107042721402013X

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  • DOI: https://doi.org/10.1134/S107042721402013X

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