Skip to main content
SpringerLink
Log in

Antioxidant Activity of 2,6-Di-tert-butylphenol Derivatives in Lipid Peroxidation and Hydrogen Peroxide Decomposition by Human Erythrocytes in vitro

  • Published:
Russian Journal of General Chemistry Aims and scope Submit manuscript

Abstract

1-(3,5-Di-tert-butyl-4-hydroxyphenyl)propane-1,2-dione dioxime and 3,5-di-tert-butyl-4-hydroxybenzohydrazide showed a high antioxidant efficiency in comparison to the known inhibitors 2,6-di-tertbutylphenol, 2,6-di-tert-butyl-4-mercaptophenol, and 2,6-di-tert-butyl-4-methylphenol (BHT), in model nonenzymatic human erythrocyte membrane lipid peroxidation.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Milei, J., Forcada, P., Fraga, C.G., Grana, D.R., Iannelli, G., Chiariello, M., Tritto, I., and Ambrosio, G., Cardiovasc. Res. 2007, vol. 73, no. 4, p. 626. doi https://doi.org/10.1016/j.cardiores.2006.12.007

    Article  CAS  Google Scholar 

  2. Novgorodtseva, T.P., Denisenko, Y.K., Zhukova, N.N., Antonyuk, M.V., Knyshova, V.V., and Gvozdenko, T.A., Lipids Health Dis. 2013, vol. 12, p. 117. doi https://doi.org/10.1186/1476-511X-12-117

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Minetti, M. and Malorni, W., Antioxid. Redox Signal. 2006, vol. 8, nos. 7–8, p. 1165. doi https://doi.org/10.1089/ars.2006.8.1165

  4. Chen, S.X. and Schopfer, R.T., Eur. J. Biochem. 1999, vol. 260, p. 726. doi https://doi.org/10.1046/j.1432-1327.1999.00199.x

    Article  CAS  PubMed  Google Scholar 

  5. Scott, M.D., Eaton, J.W., Kuypers, F.A., Chiu, D.T., and Lubin, B.H., Blood 1989, vol. 74, p. 2542.

    CAS  PubMed  Google Scholar 

  6. Martinovich, G.G. and Cherenkevich, S.N., Okislitel’novosstanovitel’nye protsessy v kletkakh (Redox Processes in Cells), Minsk: Belorus. Gos. Univ., 2008.

    Google Scholar 

  7. Chakraborty, D. and Bhattacharyya, M., Clin. Chim. Acta 2001, vol. 305, p. 123. doi https://doi.org/10.1016/S0009-8981(00)00428-9

    Article  CAS  PubMed  Google Scholar 

  8. Tesoriere, L.D., Arpa, D., Butera, D., Allegra, M., Renda, D., Maggio, A., Bongiorno, A., and Livrea, M.A., Free Radical Res. 2001, vol. 34, p. 529. doi https://doi.org/10.1080/10715760100300461

    Article  CAS  Google Scholar 

  9. Sharma, N., Biol. Med. 2014, vol. 6, no. 3, p. 1. doi https://doi.org/10.4172/0974-8369.1000214

    Article  CAS  Google Scholar 

  10. Men’shchikova, E.B., Lankin, V.Z., and Kandalintseva, N.V., Fenol’nye bioantioksidanty v biologii i meditsine (Phenolic Bioantioxidants in Biology and Medicine). Saarbrücken: LAP LAMBERT Acad., 2012.

    Google Scholar 

  11. Milaeva, E.R., Curr. Top. Med. Chem. 2011, vol. 11, no. 21, p. 2703. doi https://doi.org/10.2174/156802611798040741

    Article  CAS  PubMed  Google Scholar 

  12. Mqy, J.M., Qu, Z.-C., and Whitesell, K.R., Biochim. Biophys. Acta 1995, vol. 238, p. 127.

    Google Scholar 

  13. Rice-Evans, C., Baysal, E., Kontoghiorghes, C.A., Flynn, D.M., and Hoffbrand, A.V., Free Radical Res. Commun. 1985, vol. 1, no. 1, p. 55. doi https://doi.org/10.3109/10715768509056536

    Article  CAS  Google Scholar 

  14. Mashkovskii, M.D., Lekarstvennye sredstva (Medicines), Moscow: Novaya Volna, 2012, 16th ed.

    Google Scholar 

  15. Verbolovich, V.P., Podgornyi, Yu.K., and Podgornaya, L.M., Vopr. Med. Khim., 1989, vol. 35, no. 5, p. 35.

    CAS  Google Scholar 

  16. Boldyrev, A.A., Biokhimiya membran. Vvedenie v biokhimiyu membran (Membrane Biochemistry. Introduction to Membrane Biochemistry), Moscow: Vysshaya Shkola, 1986, p. 65.

    Google Scholar 

  17. Borisov, Yu.A., Spiridonov, V.N., and Suglubova, E.S., Klin. Lab. Diagn. 2007, no. 12, p. 36.

    Google Scholar 

  18. Halliwell, B., Clement, M.V., and Longa, L.H., FEBS Lett., 2000, vol. 486, p. 10. doi https://doi.org/10.1016/S0014-5793(00)02197-9

    Article  CAS  PubMed  Google Scholar 

  19. Nikoli-Koki, A., Blagojevi, D., and Spasi, M.B., J. Med. Biochem., 2010, vol. 29, p. 189. doi https://doi.org/10.2478/v10011-010-0018-7

    Article  CAS  Google Scholar 

  20. Gamaleya, P.A. and Klybin, P.V., Tsitologiya 1996, vol. 38, no. 12, p. 1233.

    Google Scholar 

  21. Proskurnina, E.V. and Vladimirov, Yu.A., Fundamental’nye nauki–meditsine. Biofizicheskie meditsinskie tekhnologii (Fundamental Sciences for Medicine. Biophysical Medical Technologies), Moscow: MaksPress, 2015, vol. 1, p. 37.

    Google Scholar 

  22. Bocci, V., Aldinucci, C., and Bianchi, L., Riv. Ital. Ossigeno. Ozonoterapia, 2005, no. 4, p. 30.

    Google Scholar 

  23. Berg, J.M., Kamp, J.A.F., Lubin, B.H., Roelofsen, B., and Kuypers, F.A., Free Radical Biol. Med. 1992, vol. 12, no. 6, p. 487. doi https://doi.org/10.1016/0891-5849(92)90102-M

    Article  Google Scholar 

  24. Halliwell, B. and Gutteridge, J.M.S., Free Radicals in Biology and Medicine, New York: Oxford Univ. Press 1999, p. 1.

    Google Scholar 

  25. Men’shchikova, E.B., Zenkov, N.K., Lankin, V.Z., Bondar’, I.A., and Trufakin, V.A., Okislitel’nyi stress: patologicheskie sostoyaniya i zabolevaniya (Oxidative Stress. Pathological States and Diseases), Novosibirsk: Arta 2008.

    Google Scholar 

  26. Kuznetsova, N.P., Gudkin, L.R., and Mishaeva, R.N., Sorbtsionnye Khromatogr. Protsessy 2011, vol. 11, no. 6, p. 809.

    CAS  Google Scholar 

  27. Cimen, M.Y., Clin. Chim. Acta 2008, vol. 390, p. 1. doi https://doi.org/10.1016/j.cca.2007.12.025

    Article  CAS  PubMed  Google Scholar 

  28. Milaeva, E.R., Androsova, A.V., Polyakova, O.V., Prokof’ev, A.I., and Petrosyan, V.S., Russ. Chem. Bull. 1996, vol. 45, no. 7, p. 1734. doi https://doi.org/10.1007/BF01431816

    Article  Google Scholar 

  29. Zav’yalov, I.A., Polyakova, O.V., Milaeva, E.R., and Prokof’ev, A.I, Russ. Chem. Bull., vol. 44, no. 9, p. 1725. 1996 doi https://doi.org/10.1007/BF01151299

    Google Scholar 

  30. Stroev, E.A., Makarova, V.G., and Matveeva, I.V., Praktikum po biologicheskoi khimii (Practicum on Biological Chemistry), Moscow: Meditsinskoe Informatsionnoe Agentstvo 2012, p. 351.

    Google Scholar 

  31. Zaitsev, V.G., Cand. Sci. (Biol.) Dissertation, Volgograd, 2001.

    Google Scholar 

  32. Spravochnik po klinicheskim laboratornym metodam issledovaniya (Handbook on Clinical Laboratory Research Methods), Kost, E.A., Ed., Moscow: Meditsina, 1975.

  33. Beers, R.F., Jr. and Sizer, I.W., J. Biol. Chem. 1952, vol. 195, p. 133.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Southern Scientific Center, Russian Academy of Sciences, pr. Chekhova 41, Rostov-on-Don, 344006, Russia

    M. N. Kolyada & V. P. Osipova

  2. Astrakhan State Technical University, ul. Tatishcheva 16, Astrakhan, 414025, Russia

    N. T Berberova

  3. Faculty of Chemistry, Lomonosov Moscow State University, Moscow, 119991, Russia

    D. B. Shpakovsky & E. R. Milaeva

Authors
  1. M. N. Kolyada
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. P. Osipova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. N. T Berberova
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. D. B. Shpakovsky
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. E. R. Milaeva
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to M. N. Kolyada.

Additional information

Original Russian Text © M.N. Kolyada, V.P. Osipova, N.T Berberova, D.B. Shpakovsky, E.R. Milaeva, 2018, published in Zhurnal Obshchei Khimii, 2018, Vol. 88, No. 12, pp. 1995–1999.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kolyada, M.N., Osipova, V.P., Berberova, N.T. et al. Antioxidant Activity of 2,6-Di-tert-butylphenol Derivatives in Lipid Peroxidation and Hydrogen Peroxide Decomposition by Human Erythrocytes in vitro. Russ J Gen Chem 88, 2513–2517 (2018). https://doi.org/10.1134/S1070363218120095

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1070363218120095

Keywords

Search

Navigation