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Pyranocoumarins from Zosima absinthifolia (Vent) link roots

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Abstract

Zosima absinthifolia (Vent) Link (Apiaceae) is a perennial herb indigenous to Iran. It has been used as a medicinal plant from ancient time in Iran, Turkey and Pakistan. In the present work, air-dried and powdered plant roots were extracted with n-hexane, dichloromethane and methanol, respectively, using Soxhlet apparatus. The dichloromethane extract was subjected to vacuum liquid chromatography (VLC) and preparative thin layer chromatography (P-TLC) to yield two pyranocoumarins, aegelinol and agasyllin. The antimicrobial assay was performed using agar dilution method. The results showed that purified compounds have modest to weak antibacterial and antifungal activity.

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Abbreviations

MIC:

minimum inhibitory concentration

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Authors and Affiliations

  1. Department of Biology, Faculty of Sciences, University of Mohaghegh Ardabili, Ardabil, Iran

    Seyed Mehdi Razavi

  2. Department of Chemisrty, Faculty of Sciences, University of Mohaghegh Ardabili, Ardabil, Iran

    Gholamhasan Imanzadeh & Fatemeh Soghra Jahed

  3. Department of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran

    Gholamreza Zarrini

Authors
  1. Seyed Mehdi Razavi
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  2. Gholamhasan Imanzadeh
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  3. Fatemeh Soghra Jahed
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  4. Gholamreza Zarrini
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Correspondence to Seyed Mehdi Razavi.

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Razavi, S.M., Imanzadeh, G., Jahed, F.S. et al. Pyranocoumarins from Zosima absinthifolia (Vent) link roots. Russ J Bioorg Chem 39, 215–217 (2013). https://doi.org/10.1134/S106816201301010X

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  • DOI: https://doi.org/10.1134/S106816201301010X

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