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Novel small RNAs from Mycobacterium avium

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Abstract

Posttranscriptional regulation of gene expression mediated by small RNAs plays an important role in the virulence of pathogenic microorganisms. We have detected the expression of the following Mycobacterium avium genes situated in intergenic loci and coding for small RNAs: MAV_0380-0381 (4.5S RNA), MAV_1034-1035 (trans-encoded small RNA), MAV_1415-1416 (antisense or trans-encoded small RNA), and MAV_1531-1532 (processed 5′-UTR of the 16S r\(\bar R\)NA gene). The above-named small RNAs are the first members of the small noncoding RNA class detected in M. avium.

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Abbreviations

UTR:

untranslated region

RT-PCR:

reverse transcription-PCR

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Correspondence to D. V. Ignatov.

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Original Russian Text © D.V. Ignatov, L.G. Mefodieva, K.B. Majorov, T.A. Skvortsov, T.L. Azhikina, 2012, published in Bioorganicheskaya Khimiya, 2012, Vol. 38, No. 4, pp. 509–512.

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Ignatov, D.V., Mefodieva, L.G., Majorov, K.B. et al. Novel small RNAs from Mycobacterium avium . Russ J Bioorg Chem 38, 447–449 (2012). https://doi.org/10.1134/S1068162012040085

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  • DOI: https://doi.org/10.1134/S1068162012040085

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