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Biological functions of MicroRNAs

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Abstract

The small regulatory non-coding RNA molecules, known as microRNAs (miRNAs), have been recognized as potential regulator of gene expression and modulate the gene function at the post-transcriptional level. It is now clear that miRNA biogenesis and function are related to the molecular mechanisms of various clinical diseases, which can potentially regulate every aspect of cellular activity, including differentiation and development, metabolism, proliferation, apoptotic cell death viral infection and tumorgenesis. Here, we review recent work and provide insight into the diverse roles of miRNAs.

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Authors and Affiliations

  1. Jiang Su University of Science and Technology, Zhenjiang City, 212018, Jiangsu Province, PR China

    Yong Huang, Xing Jia Shen & Qiao Ling Zhao

  2. The Key Laboratory of Silkworm and Mulberry Genetic Improvement, Ministry of Agriculture, Sericultural Research Institute, Chinese Academy of Agricultural Sciences, Zhenjiang City, 212018, Jiangsu Province, PR China

    Xing Jia Shen & Qiao Ling Zhao

  3. School of Information Science and Technology of Xiamen University, Xiamen City, 361005, Fujian Province, PR China

    Quan Zou

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  1. Yong Huang
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Correspondence to Xing Jia Shen.

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Huang, Y., Shen, X.J., Zou, Q. et al. Biological functions of MicroRNAs. Russ J Bioorg Chem 36, 684–689 (2010). https://doi.org/10.1134/S1068162010060026

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  • DOI: https://doi.org/10.1134/S1068162010060026

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