Skip to main content
SpringerLink
Log in

Parental effects of conditional mutations and their explanations

  • General Genetics
  • Published:
Russian Journal of Genetics Aims and scope Submit manuscript

Abstract

A study of the properties of conditional dominant and recessive lethals in Drosophila melanogaster has demonstrated parental effects in the inheritance and manifestation of these mutations. Maternal and paternal effects are present when conditional mutations interact with (1) one another, (2) the Y chromosome, or (3) chromosomal rearrangements, as well as (4) when the visual expression of a conditional mutation is inherited or (5) during the formation of morphoses (monstrosities) in mutant offspring. The maternal and paternal effects do not exclude one another: the same mutation can display both patterns. The characters manifesting themselves at late developmental stages (morphoses) are inherited according to a parental effect pattern. A general concept of the parental effect is proposed and its types are classified.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Khün, A., Die Pigmentirung von Habrobracon juglandis Ashmed, ihre Prädetermination und ihre Vererbung durch Gene und Plasmon, Nachr. Ges. Wiss. Göttingen, Math.-Phys. Klasse, 1927.

  2. Khün, A., Grungriß der Vererbungslehre, Heidelberg: Quelle and Meyer, 1961.

    Google Scholar 

  3. Rieger, R., Michaelis, A., and Green, M.M., A Glossary of Genetics and Cytogenetics (Classical and Molecular), Springer-Verlag, 1968, pp. 271–358.

  4. Sager, R., Cytoplasmic Genes and Organelles, New York: Academic, 1974.

    Google Scholar 

  5. Sokolov, N.N., Vzaimodeistvie yadra i tsitoplazmy pri otdalennoi gibridizatsii zhivotnykh (The Interaction of Nucleus and Cytoplasm in Distant Hybrids), Moscow: Izd. Akad. Nauk S.S.S.R., 1959.

    Google Scholar 

  6. Chong, S., Vickaryous, N., Ashe, A., et al., Modifiers of Epigenetic Reprogramming Show Paternal Effects in the Mouse, Nat. Genet., 2007, vol. 39, no. 5, pp. 614–622.

    Article  PubMed  CAS  Google Scholar 

  7. Bragina, Yu.V., Molotova, N.G., Kamysheva, E.A., et al., Revealing Drosophila Genes with Late Maternal Effect Genes, Vestn. VOGiS, 2007, vol. 11, pp. 436–444.

    Google Scholar 

  8. Chadov, B.F., Chadova, E.V., Kopyl, S.A., and Fedorova, N.B., A New Class of Mutations in Drosophila melanogaster, Dokl. Ross. Akad. Nauk, 2000, vol. 373, nos. 1–6, pp. 423–426.

    CAS  Google Scholar 

  9. Chadov, B.F., Mutations in the Regulatory Genes in Drosophila melanogaster, Biodiversity and Dynamics of Ecosystems in North Eurasia (Proc. Int. Conf.), Novosibirsk, 2000, pp. 16–18.

  10. Chadov, B.F., Chadova, E.V., Kopyl, S.A., et al., From Genetics of Intraspecific Differences to Genetics of Intraspecific Similarity, Russ. J. Genet., 2004, vol. 40, no. 9, pp. 945–958.

    Article  CAS  Google Scholar 

  11. Chadov, B.F., Chadova, E.V., Khotskina, E.A., et al., The Main Effect of Chromosomal Rearrangement Is Changing the Action of Regulatory Genes, Russ. J. Genet., 2004, vol. 40, no. 7, pp. 723–731.

    Article  CAS  Google Scholar 

  12. Chadov, B.F., Fedorova, N.B., Chadova, E.V., and Khotskina, E.A., Conditional Mutations in Drosophila, J. Life Sci., 2011, vol. 5, no. 3, pp. 224–240.

    CAS  Google Scholar 

  13. Chadov, B.F., Chadova, E.V., Kopyl, S.A., et al., Genes Controlling Development: Morphoses, Phenocopies, Dimorphs, and Other Visible Expressions of Mutant Genes, Russ. J. Genet., 2004, vol. 40, no. 3, pp. 271–280.

    Article  CAS  Google Scholar 

  14. Lindsley, D.L. and Grell, E.H., Genetic Variations of Drosophila melanogaster, Washington, DC: Carnegie Inst., 1967.

    Google Scholar 

  15. Fedorova, N.B., Chadova, E.V., Khotskina, E.A., and Chadov, B.F., Conditional Mutations in Drosophila melanogaster: Generation by Morphoses, Drozofila v eksperimental’noi genetike i biologii (Drosophila in Experimental Genetics and Biology), (Proc. Int. Conf.), Odessa, 2010, pp. 104–108.

  16. Fedorova, N.B., Chadova, E.V., Khotskina, E.A., and Chadov, B.F., Conditional Mutations: Generation by Means of Morphoses, in Faktory eksperimental’noi evolyutsii organizmov (Factors of Experimental Evolution of Organisms), Kiev: Logos, 2010, vol. 8, pp. 78–83.

    Google Scholar 

  17. Lobashev, M.E., Genetika (Genetics), Leningrad: Izd. Leningrad Gos. Univ., 1967.

    Google Scholar 

  18. Khesin, R.V., Duration of the Influence of the Maternal Genotype on the Character of the Development of the Progeny of Drosophila melanogaster, Dokl. Akad. Nauk S.S.S.R., 1948, vol. 59, no. 4, pp. 751–754.

    Google Scholar 

  19. Khesin, R.V., Maternal Effects in Drosophila melanogaster, Dokl. Akad. Nauk S.S.S.R., 1947, vol. 58, no. 4, pp. 667–670.

    Google Scholar 

  20. Chadov, B.F., Ontogenes in Drosophila melanogaster: Genetic Characteristics and the Role in Onto- and Phylogenesis, Sovremennye problemy genetiki, radiobiologii, radioekologii i evolyutsii (Modern Problems of Genetics, Radiobiology, Radioecology, and Evolution), (Proc. 2nd Int. Conf. on the Occasion of the 105th Anniversary of N.V. Timofeev-Resovsky, Erevan, 2005), Korogodina, V.L., Chin’i, A.A., and Durante, M., Eds., Dubna: Ob. inst. yad. issled., 2007, vol. 1, pp. 80–91.

    Google Scholar 

  21. Chadov, B.F., The “Image” of the Regulatory Gene in Experiments with Drosophila, Russ. J. Genet., 2002, vol. 38, no. 7, pp. 727–734.

    Article  Google Scholar 

  22. Chadov, B.F. and Fedorova, N.B., The Elementary Event of Development, Dokl. Ross. Akad. Nauk, 2003, vol. 389, no. 3, pp. 408–412.

    Google Scholar 

  23. Chadov, B.F., Facultative Dominant Lethals: Genetics, Ontogeny, and Phylogeny, Evolyutsionnaya biologiya (Evolutionary Biology), vol. 2 of Problema vida i vidoobrazovanie (The Problem of Species and Speciation), (Proc. 2nd Int. Conf., Tomsk, 2001), Stegnii, V.N., Ed., Tomsk: Tomsk Gos. Univ., 2002, pp. 118–142.

  24. Chadov, B.F., Quasicycle “Gene-Progene” as an Immanent Feature of Living Material, Filos. Nauki, 2007, vol. 32, no. 1, pp. 129–156, http://www.evolbiol.ru/large-files/chadov2007.pdf

    Google Scholar 

  25. Chadov, B.F., Quasicycle “Gene-Progene” and the Evolution, Evolyutsiya: problemy i diskussii (Evolution: Problems and Discussions), Grinin, L.E., Markov, A.V., and Korotaev, A.V., Eds., Moscow, 2010.

  26. Nusslein-Volhard, C., Maternal Effect Mutations That Alter Spatial Coordinates of the Embryo of Drosophila melanogaster, Determinants of Spatial Organization, Subtelny, S., Konigsberg, I.R., Eds., New York: Academic, 1979, pp. 185–214.Key

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090, Russia

    B. F. Chadov, N. B. Fedorova & E. V. Chadova

Authors
  1. B. F. Chadov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. N. B. Fedorova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. E. V. Chadova
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to B. F. Chadov.

Additional information

Original Russian Text © B.F. Chadov, N.B. Fedorova, E.V. Chadova, 2013, published in Genetika, 2013, Vol. 49, No. 2, pp. 164–174.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chadov, B.F., Fedorova, N.B. & Chadova, E.V. Parental effects of conditional mutations and their explanations. Russ J Genet 49, 141–150 (2013). https://doi.org/10.1134/S1022795413020038

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1022795413020038

Keywords

Search

Navigation