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Night sleep structure in the cases of disturbance of blood supply in the internal carotid artery pool

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Abstract

The study examines correlation between the degree of stenosis of the internal carotid artery (ICA) and the night sleep parameters. The possible neurophysiological mechanisms of sleep disorder in blood flow disturbances in the carotid system are also discussed. Twenty-four patients (19 men and 5 women) were examined, including 6 cases of 50% ICA stenosis, 7 cases of 50–70% ICA stenosis; and 11 cases of ICA occlusion. A polygraphic study of night sleep was conducted and the sleep stages were analyzed. The patients filled in the quality of sleep questionnaire with the presence of the somnolence scoring system. In order to assess brain perfusion, single-photon emission CT imaging of the brain was performed. The results of the study showed that the night sleep structure in the cases of 50% ICA stenosis was unchanged: all the sleep phases and stages whose quantitative parameters corresponded to the reference normal data were recorded, or only stage II sleep representation declined; in the cases of 50–70% ICA stenosis, predominantly stage II sleep and slow-wave sleep were compromised; in patients with ICA occlusion, slow-wave sleep and REM-sleep (45% of cases) were disturbed.

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References

  1. Sadykova, E.T., Levin, Ya.I., and Osetrov, A.S., Sleep disorders in patients at the acutest stage of ischemic stroke and their treatment with Zolpidem, in Son—okno v mir bodrstvovaniya (Sleep, a Window into the World of Wakefulness) (Proc. 1st Russian Conference Workshop on the Fundamental and Applied Problems of Somnology), Moscow, 2001, p. 69.

    Google Scholar 

  2. Gafurov, B.G., Interhemispheric relationships and nonspecific brain systems in cerebral stroke (clinical and encephalographic study), Doctoral (Med.) Dissertation, 1987.

    Google Scholar 

  3. Giubilei, F., Iannilli, M., Vitale, A., et al., Sleep patterns in acute stroke, Acta Neurol. Scand., 1992, vol. 86(6), p. 567.

    Article  PubMed  CAS  Google Scholar 

  4. Müller, C., Achermann, P., and Bischof, M., Visual and spectral analysis of sleep EEG in acute hemispheric stroke, Eur. Neurol., 2002, vol. 48(3), p. 164.

    Article  PubMed  Google Scholar 

  5. Levin, Ya.I. and Kovrov, G.V., Sleep disorders and their correction, Consilium Provisorum, 2003, no. 3, p. 29.

    Google Scholar 

  6. Koval’zon, V.M., Evdokimenko, A.M., Rusakova, I.M., et al., Paradoxical sleep and ischemization of the brain tissue, in Son i trevozhnost’ (Sleep and Anxiety), Verbitskii, E.V., Ed., Rostov-on-the-Don: Yzhn. Nauch. Tsentr Ross. Akad. Nauk, 2008.

    Google Scholar 

  7. Loginov, V.V., Dorokhov, V.B., Kositsyn, N.S., and Svinov, M.M., Lengthening of the paradoxical stage of sleep under the experimental ischemia conditions, in Son-okno v mir bodrstvovaniya (Sleep, a Window into the World of Wakefulness) (Proc. 1st Russian Conference Workshop on the Fundamental and Applied Problems of Somnology), Moscow, 2001, p. 47.

    Google Scholar 

  8. Loginov, V.V. and Dorokhov, V.B., Lengthening of paradoxical sleep in rats surviving the carotid artery occlusion, Zh. Vyssh. Nerv. Dyatel., 2003, vol. 53, no. 6, p. 677.

    CAS  Google Scholar 

  9. Loginov, V.V., Dorokhov, V.B., and Koval’zon, V.M., Paradoxical sleep and restorative functions of the brain tissue, Neironauki, 2007, no. 2, issue 10, p. 29.

    Google Scholar 

  10. Rusakova, I.M., Evdokimenko, A.M., Koval’zon, V.M., et al., Brain ischemization and sleep: the study using the carotid occlusion model in rats, in Son—okno v mir bodrstvovaniya (Sleep, a Window into the World of Wakefulness) (Proc. 1st Russian Conference Workshop on the Fundamental and Applied Problems of Somnology), Moscow, 2007, p. 97.

    Google Scholar 

  11. Gustov, A.V., Mel’nikova, T.V., and Guzanova, E.V., Sindromy narushenii vysshikh psikhicheskikh funktsii v nevrologicheskoi praktike: uchebnoe posobie (Syndromes of Disorders of Higher Mental Functions in Neurological Practice: A Manual), Nizhni Novgorod: Novgorod Gos. Med. Akad., 2005.

    Google Scholar 

  12. Vock, J., Achermann, P., Bischof, M., et al., Evolution of sleep and sleep EEG after hemispheric stroke, J. Sleep Res., 2002, vol. 11(4), p. 331.

    Article  PubMed  Google Scholar 

  13. Lassen, N.A., Andersen, A.R., Friberg, L., and Paulson, O.B., The retention of [99m-Tc]-d, 1-HMPAO in the human brain after intracarotid bolus injection: a kinetic analysis, J. Cerebral Blood Flow Metab., 1988, vol. 8(6), p. 13.

    Article  Google Scholar 

  14. A Manual of Standardized Terminology, Techniques, and Scoring System for Sleep Stages of Human Subjects. USPHS Publication no. 204. Rechtschaffen, A. and Kales, A., Eds., Washington: USGPO, 1968.

    Google Scholar 

  15. Sakai, K. and Crochet, S., A neural mechanism of sleep and wakefulness, Sleep Biol. Rhythms, 2003, vol. 1(1), p. 29.

    Article  Google Scholar 

  16. Siegel, J.M., REM sleep, Principles and practice of pediatric sleep medicine, Sheldon, S.H., Ferber, R., and Kryger, M.H., Eds., Amsterdam: Elsevier, 2005, 4th edition.

    Google Scholar 

  17. Stenberg, D., Neuroanatomy and neurochemistry of sleep, Cell. Mol. Life Sci., 2007, vol. 64(10), p. 1187.

    Article  PubMed  CAS  Google Scholar 

  18. Mazza, S., Soucy, J.P., Gravel, P., et al., Assessing whole brain perfusion changes in patients with REM sleep behavior disorder, Neurology, 2006, vol. 67(9), p. 1618.

    Article  PubMed  CAS  Google Scholar 

  19. Maquet, P., Delgueldre, C., Delfiore, G., et al., Functional neuroanatomy of human slow-wave sleep, J. Neurosci., 1997, vol. 17(8), p. 2807.

    PubMed  CAS  Google Scholar 

  20. Maquet, P., Peters, J.M., Aerts, J., et al., Functional neuroanatomy of human rapid eye movement sleep and dreaming, Nature, 1996, vol. 383(6596), p. 163.

    Article  PubMed  CAS  Google Scholar 

  21. Braun, A.R., Balkin, T.J., Wesenten, N.J., et al., Regional cerebral blood flow throughout the sleep wake cycle. An H2(15)O PET study, Brain, 1997, vol. 120(7), p. 1173.

    Article  PubMed  Google Scholar 

  22. Steriade, M., McCormick, D.A., and Sejnowski, T.J., Thalamocortical oscillations in the sleeping and aroused brain, Science, 1993, vol. 262(5134), p. 679.

    Article  PubMed  CAS  Google Scholar 

  23. Sumskii, L.I., Analysis of the localization of the equivalent dipole sources of the EEG phenomena of stage II night sleep, in Son — okno v mir bodrstvovaniya (Sleep, a Window into the World of Wakefulness) (Proc. 1st Russian Conference Workshop on the Fundamental and Applied Problems of Somnology), Moscow, 2001, p. 72.

    Google Scholar 

  24. Vinokurov, A.G., Krylov, V.V., Khutornoi, N.V., and Dobrovol’skii, G.F., Surgical anatomy of the cerebral arteries, Khirurgiya anevrizm golovnogo mozga: rukovodstvo v 3-kh tomakh (Surgery of Cerebral Aneurisms: Handbook in Three Volumes), Krylov, V.V., Ed., Moscow: Izd. T.A. Alekseeva, 2011, vol. 1, chapter 8, p. 220 (see p. 238 for figure).

    Google Scholar 

  25. Papuć, E., Wojczal, J., Stelmasiak, Z., and Rejdak, K., Bilateral paramedian thalamic infarction with hypothalamic dysfunction, Neurol. Neurochir. Pol., 2012, vol. 46(3), p. 279.

    PubMed  Google Scholar 

  26. Schmahmann, J.D., Vascular syndromes of the thalamus, Stroke, 2003, vol. 34(9), p. 2264.

    Article  PubMed  Google Scholar 

  27. Yavorskaya, V.A., Bondar’, O.B., Ibragimova, E.L., and Krivchun, V.M., Ischemic thalamic infarcts, Mezhd. Med. Zh., 2009, no. 1, p. 12.

    Google Scholar 

  28. Steriade, M. and Timofeev, I., Neuronal plasticity in thalamocortical networks during sleep and waking oscillations, Neuron, 2003, vol. 37(4), p. 563.

    Article  PubMed  CAS  Google Scholar 

  29. Nofzinger, E.A., Mintun, M.A., Wiseman, M.B., et al., Forebrain activation in REM sleep: an FDG PET study, Brain Res., 1997, vol. 770(1–2), p. 192.

    Article  PubMed  CAS  Google Scholar 

  30. Maquet, P., Laureys, S., Peigneux, P., et al., Experience-dependent changes in cerebral activation during human REM sleep, Nat. Neurosci., 2000, vol. 3(8), p. 831.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Sklifosovskii Research Institute of Emergency Medicine, Moscow, Russia

    I. Yu. Berezina, L. I. Sumsky & N. E. Kudryashova

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  1. I. Yu. Berezina
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  2. L. I. Sumsky
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  3. N. E. Kudryashova
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Original Russian Text © I.Yu. Berezina, L.I. Sumsky, N.E. Kudryashova, 2013, published in Fiziologiya Cheloveka, 2013, Vol. 39, No. 6, pp. 53–62.

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Berezina, I.Y., Sumsky, L.I. & Kudryashova, N.E. Night sleep structure in the cases of disturbance of blood supply in the internal carotid artery pool. Hum Physiol 39, 608–616 (2013). https://doi.org/10.1134/S0362119713060029

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  • DOI: https://doi.org/10.1134/S0362119713060029

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