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Electrophysiological heart rate regulation in patients with the Wolff-Parkinson-White phenomenon and syndrome

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The article presents the results of electrocardiography, echocardiography, heart rate variability, and nonlinear dynamics in patients with Wolff-Parkinson-White phenomenon and syndrome (WPW). Fifty-four patients were enrolled in the study; they were divided into three groups: the WPW phenomenon group, the WPW syndrome group, and the group of healthy subject. Using the mathematical models based on correlation analysis, the role of the main pathophysiological mechanisms of the formation of cardiac pathology in WPW syndrome—the disturbances of regulatory mechanisms, as well as the electrical and mechanical remodeling of the myocardium—was proven.

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Original Russian Text © I.B. Ushakov, M.V. Sharoiko, V.N. Ardashev, 2013, published in Fiziologiya Cheloveka, 2013, Vol. 39, No. 3, pp. 46–53.

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Ushakov, I.B., Sharoiko, M.V. & Ardashev, V.N. Electrophysiological heart rate regulation in patients with the Wolff-Parkinson-White phenomenon and syndrome. Hum Physiol 39, 265–271 (2013). https://doi.org/10.1134/S036211971303016X

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