Abstract
Based on real structure and optical properties of the dermis, we analyzed the possibility of polarimetric measurement of glucose content in the skin. It was shown that, at physiological concentrations of glucose in the interstitial fluid, the optical activity of glucose is not manifested in the polarization and optical properties of the tissue, since the optical activity of glucose is almost completely suppressed by the linear birefringence of the dermis.
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References
IDF Diabetes Atlas, 6th ed. (2013). www.idf.org/diabetesatlas
Amer. Diabetes Association, Diabetes Care 37 (Suppl. 1), S14 (2014).
C.-F. So, K.-S. Choi, T. K. S. Wong, and J. W. Y. Chung, Med. Dev.: Evidence Res. 5, 45 (2012).
V. V. Tuchin, Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues, (CRC, Taylor and Francis Group, London, Boca Raton, FL, 2009).
B. Rabinovitch and W. F. March, Diabetes Care 5, 254 (1982).
W. F. March, B. Rabinovitch, and R. L. Adams, Diabetes Care 5, 259 (1982).
H. Anumula, A. Nezhuvingal, Y. Li, and B. D. Cameron, Proc. SPIE-Int. Soc. Opt. Eng. 4958, 303 (2003).
B. H. Malik, C. W. Pirnstill, and G. L. Cot-, J. Biomed. Opt. 18, 017007 (2013).
G. A. Cherevatenko and E. T. Aksenov, Proc. SPIE-Int. Soc. Opt. Eng. 9031, 903105 (2014).
E. T. Aksenov, G. A. Cherevatenko, D. V. Mokrova, and V. M. Petrov, RF Patent No. 2515410 (2014).
M. C. Pierce, J. Strasswimmer, B. H. Park, B. Cense, and J. F. de Boer, J. Biomed. Opt. 9, 287 (2004).
S. Sakai, M. Yamanari, Y. Lim, S. Makita, N. Nakagawa, and Y. Yasuno, Proc. SPIE-Int. Soc. Opt. Eng. 7883, 78830Q (2011).
Yu. P. Sinichkin, D. A. Zimnyakov, D. A. Yakovlev, I. A. Ovchinnikova, A. V. Spivak, and O. V. Ushakova, Opt. Spectrosc. 101, 802 (2006).
M. F. G. Wood, N. Ghosh, E. H. Moriyama, B. C. Wilson, and I. A. Vitkin, J. Biomed. Opt. 14, 014029 (2009).
S. Jiao and L. V. Wang, J. Biomed. Opt. 7, 350 (2002).
L. I. Malinova and T. P. Denisova, in Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues, Ed. by V. V. Tuchin (CRC, Taylor Francis Group, London, Boca Raton, FL, 2009). p. 1.
S. N. Thennadil, J. L. Rennert, B. J. Wenzel, K. H. Hazen, T. L. Ruchti, and M. B. Block, Diabetes Technol. Therapeut. 3, 357 (2001).
R. C. Weast, CRC Handbook of Chemistry and Physics, 55th ed., (CRC Press, Boca Raton, FL, 1974).
L. Ryd-n, E. Standl, M. Bartnik, G. Berghe, et al., Eur. Heart J. Suppl. 9 (Suppl. C), C3 (2007).
M. F. G. Wood, X. Guo, and I. A. Vitkin, J. Biomed. Opt. 12, 014029 (2007).
R. C. Jones, J. Opt. Soc. Am. 38, 671 (1948).
R. C. Jones, J. Opt. Soc. Am. 32, 486 (1942).
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Original Russian Text © A.B. Pravdin, V.A. Spivak, D.A. Yakovlev, 2016, published in Optika i Spektroskopiya, 2016, Vol. 120, No. 1, pp. 53-58.
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Pravdin, A.B., Spivak, V.A. & Yakovlev, D.A. On the possibility of noninvasive polarimetric determination of glucose content in skin. Opt. Spectrosc. 120, 45–49 (2016). https://doi.org/10.1134/S0030400X16010161
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DOI: https://doi.org/10.1134/S0030400X16010161