Abstract
Phytogenous Phenolic and benzene compounds have been described as being responsible for many biological activities including antifungal effects. The effect of caffeine and cinnamic and caffeic acids on a model fungus, Aspergillus nidulans, was investigated at its initial stage of germination. Conidia did not germinate in the presence of cinnamic acid (1 mM). Caffeine and caffeic acid exerted a negative effect on germination, on the nuclear duplication cycle and on first septum formation. The effects of caffeine were dose-dependent; effects of caffeic acid (1 mM) were more intense than those of caffeine (10 mM).
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Yuvamoto, P.D., Said, S. Germination, duplication cycle and septum formation are altered by caffeine, caffeic acid and cinnamic acid in Aspergillus nidulans . Microbiology 76, 735–738 (2007). https://doi.org/10.1134/S0026261707060136
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DOI: https://doi.org/10.1134/S0026261707060136