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Antitumor action and other regulatory effects of low-intensity electromagnetic and chemical factors in an experiment

  • Complex Systems Biophysics
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Abstract

This paper presents a brief overview of the results of original research of biological responses to the effect of low doses of substances exhibiting cytostatic and regulatory effects, as well as to weak electromagnetic radiation of different frequency ranges. The possibility of obtaining pronounced antitumor, antistress, and geroprotective effects was shown. The relation between the systemic mechanisms of implementation of these effects and structural rearrangements in biological fluids, as well as areas that seem promising for optimization of the therapeutic properties of informational effect, are discussed.

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References

  1. E. B. Burlakova, A. A. Konradov, and E. L. Mal’tseva, Biophysics (Moscow) 49(3), 522 (2004).

    Google Scholar 

  2. O. V. Betskii, N. N. Lebedeva, and Yu. G. Yaremenko, Biomed. Tekhnol. Radioelektr., Nos. 2–4, 20 (2007).

    Google Scholar 

  3. L. Kh. Garkavi, E. B. Kvakina, T. S. Kuz’menko, and A. I. Shikhlyarova, Antistress Reactions and Activation Therapy (Yekaterinburg, 2003).

    Google Scholar 

  4. V. I. Lobyshev, Ross. Khim. Zh. 57(1), 107 (2007).

    Google Scholar 

  5. A. K. Lyashchenko, Biomed. Radioelektr., Nos. 8–9, 62 (2007).

    Google Scholar 

  6. N. P. Kareva, T. I. Pospelova, S. V. Pozdnyakova, et al., Byull. Sib. Med., Suppl. 3, 105 (2008).

    Google Scholar 

  7. . S. M. Kechedzhieva, A. I. Shikhlyarova, L. P. Barsukova, et al., Palliativn. Med. Rabilitatsiya, No. 1, 64 (2010).

    Google Scholar 

  8. J. R. Salvatore, J. Harrington, and T. Kummet, Bioelectromagnetics 24(7), 524 (2003).

    Article  Google Scholar 

  9. L. Kh. Garkavi, M. A. Ukolova, and E. B. Kvakina, in Discoveries in the Soviet Union (Moscow, 1975), No. 3, pp. 56–61 [in Russian].

    Google Scholar 

  10. V. P. Konoplev, in Models and Methods of Experimental Oncology (Moscow, 1960), pp. 44–162.

    Google Scholar 

  11. G. B. Pliss, Byull. Eksp. Biol. Med., No. 2, 95 (1961).

    Google Scholar 

  12. R. A. Kopaladze, Bioethics. Experiments on Animals: History, Current State, and Prospects (Sputnik+, Moscow, 2003).

    Google Scholar 

  13. G. I. Kulik, Vopr. Onkol., No. 7, 778 (1986).

    Google Scholar 

  14. L. Kh. Garkavi, E. B. Kvakina, A. K. Mulatova, and A. I. Shikhlyarova, Vopr. Onkol. 26(6), 48 (1980).

    Google Scholar 

  15. L. Kh. Garkavi, E. B. Kvakina, A. K. Mulatova, and F. M. Taras’yants, Vopr. Onkol. 27(7), 61 (1981).

    Google Scholar 

  16. L. Kh. Garkavi, E. B. Kvakina, A. I. Shikhlyarova, et al., Biofizika 41(4), 898 (1996).

    Google Scholar 

  17. S. Osinski and P. Vaupel’, Microphysiology of Tumors (Naukova Dumka, Kiev, 2009) [in Russian].

    Google Scholar 

  18. E. A. Korneva, A Primer in Immunophysiology (St. Petersburg, 2003) [in Russian].

    Google Scholar 

  19. L. V. Onoprienko, Russ. J. Bioorg. Chem. 37(4), 387 (2011).

    Article  Google Scholar 

  20. W. R. Adey, Proc. IEEE 68(1), 119 (1980).

    Article  Google Scholar 

  21. O. V. Khabarova, Biomed. Tekhnol. Radioelectr., No. 5, 56 (2002).

    Google Scholar 

  22. L. A. Sevast’yanova, in Non-Heat Effects of Millimeter Wave Radiation on Biological Objects (1983), pp. 48–62 [in Russian].

    Google Scholar 

  23. G. V. Zhukova, L. Kh. Garkavi, E. Yu. Zlatnik, and O. F. Evstratova, Millimetr. Volny Biol. Med., No. 4, 3 (2005).

    Google Scholar 

  24. G. V. Zhukova, L. Kh. Garkavi, A. I. Shikhlyarova, et al., Biomed. Tekhnol. Radioelectr., Nos. 1–2, 10 (2005).

    Google Scholar 

  25. V. I. Petrosyan, JETP Lett. 31(23), 29 (2005).

    Google Scholar 

  26. T. N. Gudtskova, G. V. Zhukova, L. Kh. Garkavi, et al., Byull. Eksp. Biol. Med. 150(11), 593 (2010).

    Google Scholar 

  27. A. Yu. Budantsev, Monoaminergic Systems of the Brain (Nauka, Moscow, 1976) [in Russian].

    Google Scholar 

  28. F. Nyberg and M. Hallberg, Methods Mol. Biol. 789, 191 (2011).

    Article  Google Scholar 

  29. A. A. Starchenko, V. A. Khil’ko, S. A. Komarets, et al., Immunologiya, No. 4, 250 (2002).

    Google Scholar 

  30. L. Kh. Garkavi and A. I. Shikhlyarova, in Prospects for Development of Scientific Research in the Coming Century (Rostov-on-Don, 2001), pp. 302–308 [in Russian].

    Google Scholar 

  31. L. Kh. Garkavi, G. V. Zhukova, P. G. Sakun, et al., RF Patent No. 2475865 (20 February 2014).

  32. E. Davenas, F. Beauvais, J. Arnara, et al., Nature 333(6176), 816 (1988).

    Article  ADS  Google Scholar 

  33. A. P. Golubev, E. I. Lyublina, N. A. Tolokontsev, and V. A. Filov, Quantitative Toxicology (Meditsina, Leningrad, 1973) [in Russian].

    Google Scholar 

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Correspondence to L. H. Garkavi.

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Original Russian Text © L.H. Garkavi, G.V. Zhukova, A.I. Shikhliarova, O.F. Evstratova, T.A. Barteneva, T.N. Gudzkova, M.I. Bragina, N.M. Maschenko, S.V. Grigorov, P.G. Sakun, 2014, published in Biofizika, 2014, Vol. 59, No. 6, pp. 1161–1172.

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Garkavi, L.H., Zhukova, G.V., Shikhliarova, A.I. et al. Antitumor action and other regulatory effects of low-intensity electromagnetic and chemical factors in an experiment. BIOPHYSICS 59, 944–953 (2014). https://doi.org/10.1134/S0006350914060037

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