Skip to main content
SpringerLink
Log in

Circahoralian (Ultradian) metabolic rhythms

  • Review
  • Published:
Biochemistry (Moscow) Aims and scope Submit manuscript

Abstract

This review presents data concerning metabolic rhythms with periods close to one hour (20 to 120 min): their occurrence, biochemical organization, nature, and significance for adaptations and age-related changes of cells and organs. Circahoralian (ultradian) rhythms have been detected for cell mass and size, protein synthesis, enzyme activities, concentration of ATP and hormones, cell respiration, and cytoplasm pH. Rhythms have been observed in bacteria, yeasts, and protozoa, as well as in many cells of metazoans, including mammals, in vivo and in cell cultures. In cell populations, the rhythms are organized by direct cell-cell communication. The biochemical mechanism involves membrane signal factors and cytoplasmic processes resulting in synchronization of individual oscillations to a common rhythm. Phosphorylation of proteins is the key process of coordination of protein synthesis and enzyme activity kinetics. The fractal nature of circahoralian rhythms is discussed as well as the involvement of these rhythms in adaptations of the cells and organs. Senescent decrease in rhythm amplitudes and correspondingly in cell-cell communication has been observed. The possibility of remodeling these changes through the intercellular medium has been predicted and experimentally shown. Perspectives for studies of the organizers and disorganizers of cell-cell communication in the intercellular medium along with appropriate receptors are discussed with special emphasis on aging and pathology. One perspective can be more precise definition of the range of normal biochemical and physiological state with the goal of correction of cellular functions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Brodsky, V. Y., and Kuznetsova, A. F. (1961) Tsitologiya, 3, 89–92.

    Google Scholar 

  2. Brodsky, V. Y. (1970) in Works of 5 Histochem. Conf. [in Russian], Tbilisi, pp. 114–128.

    Google Scholar 

  3. Brodsky, V. Y., and Nechaeva, N. V. (1973) Tsitologiya, 15, 52–59.

    Google Scholar 

  4. Brodsky, V. Y. (1975) J. Theor. Biol., 55, 157–200.

    Google Scholar 

  5. Lloyd, D., and Rossi, E. L. (eds.) (1992) Ultradian Rhythms in Life Processes, Springer-Verlag, London.

    Google Scholar 

  6. Lloyd, D., and Rossi, E. L. (eds.) (2008) Ultradian Rhythms from Molecules to Mind, Springer-Verlag, London-NY.

    Google Scholar 

  7. Brodsky, V. Y., Zaguskin, S. L., and Lebedev, E. A. (1977) Tsitologiya, 19, 931–934.

    Google Scholar 

  8. Litinskaya, L. L., Ogloblina, T. A., Veksler, A. M., Agroskin, L. S., Papayan, G. V., Khrust, Yu. R., and Eydus, L. Kh. (1982) Tsitologiya, 24, 1215–1222.

    Google Scholar 

  9. Kosykh, M. I., and Chentsov, Yu. S. (1991) Doklady RAN, 316, 475–478.

    CAS  Google Scholar 

  10. Skulachev, V. P. (1989) Energetics of Biological Membranes [in Russian], Nauka, Moscow.

    Google Scholar 

  11. Edwards, S. W., and Lloyd, D. (1980) FEBS Lett., 109, 21–26.

    CAS  PubMed  Google Scholar 

  12. Lloyd, D., Edwards, S. W., and Fry, J. C. (1982) Proc. Natl. Acad. Sci. USA, 79, 3785–3788.

    CAS  PubMed Central  PubMed  Google Scholar 

  13. Lloyd, D., Poole, R. K., and Edwards, S. W. (1982) The Cell Division Cycle: Temporal Control of Cellular Growth and Reproduction, Academic Press, London.

    Google Scholar 

  14. Ferreira, G. M. N., Hammond, K. D., and Gilbert, D. A. (1994) Biosystems, 32, 183–190.

    CAS  PubMed  Google Scholar 

  15. Novikova, T. Ye., and Borovkov, A. Yu. (1987) Tsitologiya, 29, 236–239.

    CAS  Google Scholar 

  16. Bodalina, U. M., Hammond, K. D., and Gilbert, D. A. (2007) Mol. Cell Biochem., 294, 155–162.

    CAS  PubMed  Google Scholar 

  17. Geva-Zatorsky, N., Rosenfeld, N., Itzkovitz, S., Milo, R., Sigal, A., Dekel, E., Liron, Y., Polak, P., Lahav, G., and Alon, U. (2006) Mol. Syst. Biol., 2, 13550–13555.

    Google Scholar 

  18. Hat, B., Puszynski, K., and Lipniacki, T. (2009) IET Syst. Biol., 3, 342–355.

    CAS  PubMed  Google Scholar 

  19. Costero, J., Chevez, A., Peralta, L., Monroy, E., and Ramon, F. (1965) Texas Rep. Biol. Med., 23, 213–220.

    Google Scholar 

  20. Mityushin, V. M., Litinskaya, L. L., and Kaminir, L. B. (1967) Biofizika, 12, 89–96.

    Google Scholar 

  21. Veksler, A. M., Kostenko, G. A., Eydus, L. Kh., and Litinskaya, L. L. (1973) in Scanning Technique in the Study of Cell Populations (Ivanitsky, ed.) [in Russian], Pushchino-on-Oka, pp. 101–112.

  22. Svanidze, I. K., and Didimova, Ye. V. (1974) Tsitologiya, 16, 187–192.

    CAS  Google Scholar 

  23. Kostenko, G. A., Litinskaya, L. L., Veksler, A. M., and Eydus, L. Kh. (1975) Doklady AN SSSR, 211, 714–717.

    Google Scholar 

  24. Brodsky, V. Y. (2006) Biol. Rev. Cambridge Phylosoph. Soc., 82, 143–162.

    Google Scholar 

  25. Brodsky, V. Y., Terskikh, V. V., Vasiliev, A. V., Zvezdina, N. D., Vorotelyak, Ye. A., Fateeva, V. I., and Malchenko, L. A. (2011) Ontogenez, 4, 312–319.

    Google Scholar 

  26. Boykov, P. Ya. (1987) Mechanisms of Cell Cycle Initiation: Doctoral dissertation [in Russian], ICP AS, Moscow.

    Google Scholar 

  27. Brodsky, V. Y., Boikov, P. Y., Nechaeva, N. V., Yurovitsky, Y. G., Novikova, T. E., Fateeva, V. I., and Shevchenko, N. A. (1992) J. Cell Sci., 103, 363–370.

    PubMed  Google Scholar 

  28. Kuempel, P. L., Masters, M., and Pardee, A. B. (1965) Biochem. Biophys. Res. Commun., 18, 858–867.

    CAS  Google Scholar 

  29. Knorre, W. A. (1968) in Biological and Biochemical Oscillators (Chance, B., Pye, E. K., and Ghosh, A. K., eds.) Academic Press, NY, pp. 449–455.

  30. Masters, M., and Donachie, W. D. (1966) Nature, 209, 476–479.

    CAS  PubMed  Google Scholar 

  31. Boddy, A., Clark, P. H., Houldsworth, M. A., and Lilly, M. D. (1967) J. Gen. Microbiol., 48, 137–145.

    CAS  Google Scholar 

  32. Lloyd, D., Salgado, L. E., Turner, M. P., Suller, M. T. E., and Murray, D. (2002) Microbiology, 148, 3715–3724.

    CAS  PubMed  Google Scholar 

  33. Michel, U., and Hardeland, R. (1985) J. Interdiscipl. Cycle Res., 16, 17–23.

    CAS  Google Scholar 

  34. Lloyd, D. (1992) in Ultradian Rhythms in Life Processes (Lloyd, D., and Rossi, E. L., eds.) Springer, London, pp. 5–22.

  35. Holvorson, H. O., Bock, R. M., Tauro, P., Epstein, R., and Laberge, M. (1966) in Cell Synchrony (Cameron, I. L., and Padilla, G. M., eds.) Academic Press, NY-London, pp. 102–116.

  36. Mano, Y. (1970) Devel. Biol., 22, 433–460.

    CAS  Google Scholar 

  37. Petzelt, C. (1972) Exp. Cell Res., 70, 333–339.

    CAS  PubMed  Google Scholar 

  38. Yarygin, K. N., Nechaeva, N. V., Fateeva, V. I., Novikova, T. Ye., and Brodsky, V. Y. (1978) Byul. Eksp. Biol. Med., 86, 726–728.

    CAS  Google Scholar 

  39. Hammond, K. D., Wollbrandt, R. K., and Gilbert, D. A. (1985) Int. J. Biochem., 17, 259–264.

    CAS  PubMed  Google Scholar 

  40. Hammond, K. D., Cloutman, L., Mindel, B., and Gilbert, D. A. (1989) Int. J. Biochem., 21, 197–201.

    CAS  PubMed  Google Scholar 

  41. Hammond, K. D., Bhoola, R., Bodalina, U., and Gilbert, D. A. (1998) Trends Comp. Biochem. Physiol., 4, 75–88.

    CAS  Google Scholar 

  42. Hammond, K. D., Savage, N., and Littlewood, M. (2000) Cell Biol. Int., 24, 549–557.

    CAS  PubMed  Google Scholar 

  43. Calvert-Evers, J. L., and Hammond, K. D. (2002) Cell Biol. Int., 26, 1035–1042.

    CAS  PubMed  Google Scholar 

  44. Bodalina, U. M., Hammond, K. D., and Gilbert, D. A. (2005) Cell Biol. Int., 29, 287–299.

    CAS  PubMed  Google Scholar 

  45. Kippert, F. (1996) Chronobiol. Int., 13, 1–13.

    CAS  PubMed  Google Scholar 

  46. Murray, D., Klevecz, R. R., and Lloyd, D. (2003) Exp. Cell Res., 287, 10–15.

    CAS  PubMed  Google Scholar 

  47. Murray, D. B., Roller, S., Kuriyama, H., and Lloyd, D. (2001) J. Bacteriol., 183, 7253–7259.

    CAS  PubMed Central  PubMed  Google Scholar 

  48. Litinskaya, L. L., Ogloblina, T. A., Veksler, A. M., Agroskin, L. S., Papayan, G. V., Khrust, Yu. R., and Eydus, L. Kh. (1982) Tsitologiya, 24, 1215–1222.

    Google Scholar 

  49. Litinskaya, L. L., Veksler, A. M., Nechaeva, N. V., Novikova, T. Ye., Fateeva, V. I., and Brodsky, V. Y. (1987) Tsitologiya, 29, 917–921.

    CAS  Google Scholar 

  50. Droste, K., De Groote, L., Lightman, S. L., Reul, J. M., and Linthorst, A. C. (2009) J. Endocrinol., 21, 132–140.

    CAS  Google Scholar 

  51. Lightman, S. L., Wiles, C. C., Atkinson, H. C., Henley, D. E., Russell, G. M., Leendertz, J. A., McKenna, M. A., Spiga, F., Wood, S. A., and Conway-Campbell, B. L. (2008) Eur. J. Pharmacol., 583, 255–262.

    CAS  PubMed  Google Scholar 

  52. Lefcourt, A. M., Bitman, J., Kahl, S., and Wood, D. L. (1993) J. Dairy Sci., 76, 2607–2612.

    CAS  PubMed  Google Scholar 

  53. Bergendahl, M., Evans, W. S., and Veldhuis, J. D. (1996) Human Reprod. Update, 2, 507–518.

    CAS  Google Scholar 

  54. Backstrom, C. T., McNeilly, A. S., Leask, R. M., and Baird, D. T. (1982) Clin. Endocrinol., 16, 29–42.

    Google Scholar 

  55. Dunkel, L., Alfthan, H., and Stenman, U. H. (1990) Pediatr. Res., 27, 215–219.

    CAS  PubMed  Google Scholar 

  56. Schlatt, S., Pohl, C. R., Ehmcke, J., and Ramaswamy, S. (2008) Biol. Reprod., 79, 93–99.

    CAS  PubMed  Google Scholar 

  57. Geoffriau, M., Claustrat, B., and Veldhuis, J. (1999) J. Pineal Res., 27, 139–144.

    CAS  PubMed  Google Scholar 

  58. Oz-Hoyos, A., Jaldo, R., Molina-Carballo, A., Escames, G., Fernandez-Garcia, J. M., and Reiter, J. (2001) J. Clin. Endocrinol. Metab., 86, 1181–1187.

    Google Scholar 

  59. Matthews, D. R., Naylor, B. A., and Jones, R. G. (1983) Diabetes, 37, 617–621.

    Google Scholar 

  60. Schaefer, A., Simon, C., Frank, A. V., Piquard, O., Geny, B., and Brandenberger, G. (2003) Diabetes Care, 26, 168–171.

    CAS  PubMed  Google Scholar 

  61. Otukonyong, E. E., Dube, M. G., Torto, R., Kalra, P. S., and Kalra, S. P. (2005) Peptides, 26, 2559–2566.

    CAS  PubMed  Google Scholar 

  62. Rossmanith, W. G., Laughlin, G. A., and Mortola, J. F. (1990) J. Clin. Endocrinol. Metab., 70, 990–995.

    CAS  PubMed  Google Scholar 

  63. Gronfier, C., and Brandenberger, G. (1998) Sleep Med. Rev., 2, 17–29.

    CAS  PubMed  Google Scholar 

  64. Tannenbaum, G., and Martin, J. (2011) Endocrinology, 98, 562–570.

    Google Scholar 

  65. Togo, F., Natelson, B. H., Adler, G. K., Ottenweller, J. E., Goldenberg, D., Struzik, Z., and Yamamoto, Y. (2009) Exp. Biol. Med., 234, 232–240.

    CAS  Google Scholar 

  66. Ichikawa, T. (2001) Zool. Sci., 18, 151–158.

    CAS  Google Scholar 

  67. Rott, N. N. (1984) Ontogenez, 15, 5–19.

    CAS  PubMed  Google Scholar 

  68. Mano, Y. (1975) Biosystems, 7, 51–65.

    CAS  PubMed  Google Scholar 

  69. Mano, Y., Suzuki, N., and Shimatake, H. (1977) Growth Differentiation, 19, 31–39.

    CAS  Google Scholar 

  70. Yasumasu, I., Fujiwara, A., and Ishida, K. (1973) Biochem. Biophys. Res. Commun., 54, 628–632.

    CAS  PubMed  Google Scholar 

  71. Gelfand, I. M., and Tsetlin, M. L. (1960) Doklady AN SSSR, 131, 1242–1245.

    Google Scholar 

  72. Brodsky, V. Y., Nechaeva, N. V., Novikova, T. E., and Gvazava, I. G. (1994) Izvest. AN, Ser. Biol., 6, 853–858.

    Google Scholar 

  73. Brodsky, V. Y., Nechaeva, N. V., Zvezdina, N. D., Prokazova, N. V., Golovanova, N. K., Novikova, T. E., Gvasava, I. G., and Fateeva, V. I. (2000) Cell Biol. Int., 24, 211–222.

    CAS  PubMed  Google Scholar 

  74. Brodsky, V. Y., Zvezdina, N. D., Nechaeva, N. V., Novikova, T. E., Gvasava, I. G., Fateeva, V. I., and Gracheva, H. (2003) Cell Biol. Int., 27, 935–942.

    CAS  PubMed  Google Scholar 

  75. Brodsky, V. Y., Zvezdina, N. D., Nechaeva, N. V., Avdonin, P. V., Novikova, T. E., Gvasava, I. G., Fateeva, V. I., and Malchenko, L. A. (2003) Cell Biol. Int., 27, 965–976.

    CAS  PubMed  Google Scholar 

  76. Brodsky, V. Y., Nechaeva, N. V., Zvezdina, N. D., Novikova, T. E., Gvasava, I. G., Fateeva, V. I., and Malchenko, L. A. (2004) Cell Biol. Int., 28, 311–316.

    CAS  PubMed  Google Scholar 

  77. Brodsky, V. Y., Zvezdina, N. D., Nechaeva, N. V., Novikova, T. E., Gvasava, I. G., Fateeva, V. I., and Malchenko, L. A. (2005) Cell Biol. Int., 29, 971–975.

    CAS  PubMed  Google Scholar 

  78. Brodsky, V. Y., Zvezdina, N. D., Fateeva, V. I., and Malchenko, L. A. (2007) Cell Biol. Int., 31, 65–73.

    CAS  PubMed  Google Scholar 

  79. Zvezdina, N. D., Malchenko, L. A., Fateeva, V. I., and Brodsky, V. Y. (2008) Ontogenez, 39, 198–207.

    CAS  PubMed  Google Scholar 

  80. Brodsky, V. Y., and Zvezdina, N. D. (2010) Cell Biol. Int., 34, 1199–1204.

    CAS  PubMed  Google Scholar 

  81. Dyatlovitskaya, E. V. (1992) Biokhimiya, 57, 1004–1010.

    CAS  Google Scholar 

  82. Brodsky, V. Y., Vasiliev, A. V., Terskikh, V. V., Zvezdina, N. D., Fateeva, V. I., Malchenko, L. A., Kiseleva, E. V., and Bueverova, E. I. (2012) J. Cell Tissue Res., 12, 3157–3162.

    CAS  Google Scholar 

  83. Jin, J., and Pawson, T. (2012) Philos. Trans R Soc. Lond. B Biol. Sci., 367, 2540–2555.

    CAS  PubMed Central  PubMed  Google Scholar 

  84. Gilbert, D. A., and Hammond, K. D. (2008) in Ultradian Rhythms from Molecules to Mind (Lloyd, D., and Rossi, E. L., eds.) Springer-Verlag, London-NY, pp. 105–128.

  85. Brodsky, V. Y., Konchenko, D. S., Zvezdina, N. D., Malchenko, L. A., and Dubovaja, T. K. (2012) J. Cell Tissue Res., 12, 3265–3271.

    CAS  Google Scholar 

  86. Brodsky, V. Y., Dubovaya, T. K., Nechaeva, N. V., Fateeva, V. I., Novikova, T. E., and Gvazava, I. G. (1995) Izvest. AN, Ser. Biol., 2, 133–136.

    Google Scholar 

  87. Brodsky, V. Y., Nechaeva, N. V., Novikova, T. E., Gvazava, I. G., and Fateeva, V. I. (1995) Izvest. AN, Ser. Biol., 5, 517–520.

    Google Scholar 

  88. Nakamura, Y., Hishimoto, Y., Yamakawa, T., and Suzuki, A. (1988) J. Biochem., 103, 396–398.

    CAS  PubMed  Google Scholar 

  89. Ozkok, E., Cendiz, S., and Guevener, B. (1999) J. Basic Clin. Physiol. Pharmacol., 10, 337–344.

    CAS  PubMed  Google Scholar 

  90. Prozorovskaya, M. P. (1983) Fiziol. Zh. SSSR, 69, 1244–1246.

    CAS  Google Scholar 

  91. Brodsky, V. Y., Nechaeva, N. V., Zvezdina, N. D., Novikova, T. Ye., Gvazava, I. G., Fateeva, V. I., and Malchenko, L. A. (2003) Izvest. AN, Ser. Biol., 6, 650–657.

    Google Scholar 

  92. Mandelbrot, B. B. (1980) The Fractal Geometry of Nature, Freeman, NY.

    Google Scholar 

  93. Feder, Ye. (1991) Fractals [Russian translation], Mir, Moscow.

    Google Scholar 

  94. Lloyd, A. L., and Lloyd, D. (1993) Biosystem, 29, 77–85.

    CAS  Google Scholar 

  95. Bunde, A., and Havlin, S. (1994) Fractals in Science, Springer, New York-London.

    Google Scholar 

  96. Goldbeter, A. (1996) Biochemical Oscillations and Cellular Rhythms: the Molecular Basis of Periodic and Chaotic Behaviour, Cambridge University Press, Cambridge.

    Google Scholar 

  97. Lloyd, D., and Kippert, F. (1987) in Temperature and Animal Cells (Bowler, K., and Fuller, B. J., eds.) Cambridge University Press, Cambridge.

  98. Lloyd, D., and Kippert, F. (1993) Cell Biol. Int., 17, 1047–1052.

    CAS  PubMed  Google Scholar 

  99. Mano, Y. (1968) Biochem. Biophys. Res. Commun., 33, 877–882.

    CAS  PubMed  Google Scholar 

  100. Kharazova, A. D. (1999) Cytological Basis of Marine Molluscs Adaptation to Salinity Changes: Doctoral dissertation [in Russian], St. Petersburg University, St. Petersburg.

    Google Scholar 

  101. Brodsky, V. Y., Nechaeva, N. V., and Prilutsky, V. I. (1973) Tsitologiya, 15, 177–182.

    Google Scholar 

  102. Ferreira, G. M., Hammond, K. D., and Gilbert, D. A. (1996) Cell Biol. Int., 20, 625–633.

    CAS  PubMed  Google Scholar 

  103. Goldberger, A. L., and West, B. J. (1987) Ann. NY Acad. Sci., 504, 195–213.

    CAS  PubMed  Google Scholar 

  104. Garfinkel, A., Spano, M. L., Ditto, W. L., and Weiss, J. N. (1992) Science, 257, 1230–1235.

    CAS  PubMed  Google Scholar 

  105. Skinner, J. E., Goldberger, A. L., Mayer-Kress, G., and Ideker, R. F. (1990) Biotechnology, 8, 1018–1024.

    Google Scholar 

  106. Szeto, H., Dwyer, G., Cheng, P., and Decena, J. (1990) Proc. Conf. IEEE Medicine and Biology, 12, 1390–1391.

    Google Scholar 

  107. Pool, R. (1989) Science, 243, 604–607.

    CAS  PubMed  Google Scholar 

  108. Elbert, T., Ray, W. J., Kovalic, Z. J., Skinner, J. E., Graf, K. E., and Birbaumer, N. (1994) Physiol. Rev., 74, 1–47.

    CAS  PubMed  Google Scholar 

  109. Kleitman, N. (1963) Sleep and Wakefulness, University of Chicago Press, Chicago.

    Google Scholar 

  110. Kobayashi, T. Y. (1988) EEG Clin. Neurophysiol., 70, 110–117.

    Google Scholar 

  111. Daan, S., and Slopsema, S. (1978) J. Comp. Physiol., 127, 215–227.

    Google Scholar 

  112. Delgado-Garcia, I. M., Gran, C., and De Feudis, P. (1976) Exp. Brain Res., 25, 79–91.

    CAS  PubMed  Google Scholar 

  113. Murell, K. F. (1971) in Biological Rhythms and Human Performance (Colquhoun, W. P., ed.) Academic Press, London-NY, pp. 241–272.

  114. Brodsky, V. Y., Rapoport, S. I., Fateeva, V. I., Nechaeva, N. V., Kharayan, L. V., and Rasulov, M. I. (1984) BEBM, 5, 612–614.

    Google Scholar 

  115. Brodsky, V. Y., Komarov, F. I., and Rapoport, S. I. (2007) Klin. Med., 5, 4–10.

    Google Scholar 

  116. Zaguskin, S. L., Grinchenko, S. N., and Brodsky, V. Y. (1991) Izvest. AN, Ser. Biol., 6, 950–954.

    Google Scholar 

  117. Brodsky, V. Y. (1992) in Ultradian Rhythms in Life Processes (Lloyd, D., and Rossi, E., eds.) Springer, London, pp. 23–40.

  118. Anisimov, V. N., Popovich, I. G., Zaberzhinski, M. A., Anisimov, S. V., Vesnushkin, G. M., and Vinogradova, I. A. (2006) Biochim. Biophys. Acta, 1757, 573–589.

    CAS  PubMed  Google Scholar 

  119. Shnol, S. E. (1979) Physicochemical Factors of Biological Evolution [in Russian], Nauka, Moscow.

    Google Scholar 

  120. Buznikov, G. A. (1967) Low Molecular Regulators of Development [in Russian], Nauka, Moscow.

    Google Scholar 

  121. Buznikov, G. A. (1987) Neurotransmitters in Embryogenesis [in Russian], Nauka, Moscow.

    Google Scholar 

  122. Sakharov, D. A. (1991) in Early Brain (Gustavson, M., and Reuter, M., eds.) Abo Academic Press, Abo, pp. 73–88.

  123. Ugrumov, M. V. (2002) Microsc. Res. Tech., 56, 164–171.

    CAS  PubMed  Google Scholar 

  124. Pronina, T., Adamskaya, E., Ugrumov, M., Kuznetsova, T., Shishkina, I., Babichev, V., Calas, A., Tramu, G., Mailly, P., and Makarenko, I. (2003) J. Neuroendocrinol., 15, 549–558.

    CAS  PubMed  Google Scholar 

  125. Voronezhskaya, E. E., Khabarova, M. Yu., and Nezlin, L. P. (2004) Development, 131, 3671–3680.

    CAS  PubMed  Google Scholar 

  126. Oleskin, A. V. (2001) Biopolitics [in Russian], MSU, Moscow.

    Google Scholar 

  127. Oleskin, A. V., and Kirovskaya, T. A. (2007) Vestnik RAN, 77, 139–148.

    Google Scholar 

  128. Brodsky, V. Y., and Lloyd, D. (2008) in Ultadian Rhythms from Molecules to Mind (Lloyd D., and Rossi, E., eds.) Springer, London, pp. 85–104.

  129. Harper, N., Hughes, M. A., Farrow, S. N., Cohen, G. M., and MacFarlane, M. (2003) J. Biol. Chem., 278, 44338–44347.

    CAS  PubMed  Google Scholar 

  130. Sanchez, V., Lucas, M., Sanz, A., and Goberna, R. (1992) Biosci. Rep., 12, 199–206.

    CAS  PubMed  Google Scholar 

  131. Bektas, M., and Spiegel, S. (2004) Glycoconj. J., 20, 39–47.

    CAS  PubMed  Google Scholar 

  132. Segui, B., Andrieu-Abadie, N., Jaffrezou, J. P., Benoist, H., and Levade, T. (2006) Biochim. Biophys. Acta, 1758, 2104–2120.

    CAS  PubMed  Google Scholar 

  133. Fouquet, S., Lugo-Martinez, V. N., Faussat, A. M., Renaud, F., and Cardot, P. (2004) J. Biol. Chem., 279, 43061–43069.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Koltsov Institute of Developmental Biology, Russian Academy of Sciences, ul. Vavilova 26, 117808, Moscow, Russia

    V. Y. Brodsky

Authors
  1. V. Y. Brodsky
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to V. Y. Brodsky.

Additional information

Original Russian Text © V. Y. Brodsky, 2014, published in Biokhimiya, 2014, Vol. 79, No. 6, pp. 619–632.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Brodsky, V.Y. Circahoralian (Ultradian) metabolic rhythms. Biochemistry Moscow 79, 483–495 (2014). https://doi.org/10.1134/S0006297914060017

Download citation

  • Received:

  • Revised:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S0006297914060017

Key words

Search

Navigation