Nanoplasmonics as nanofluidics: transport and sensing in flowthrough nanohole arrays

Carlos Escobedo; Alexandre G. Brolo; Reuven Gordon; David Sinton

doi:10.1117/12.875848

14 February 2011 Nanoplasmonics as nanofluidics: transport and sensing in flowthrough nanohole arrays

Carlos Escobedo, Alexandre G. Brolo, Reuven Gordon, David Sinton

Proceedings Volume 7929, Microfluidics, BioMEMS, and Medical Microsystems IX; 79290Q (2011) https://doi.org/10.1117/12.875848
Event: SPIE MOEMS-MEMS, 2011, San Francisco, California, United States

Abstract

Metallic nanohole arrays support surface electromagnetic waves that enable enhanced optical transmission and may be exploited for sensing. Our group has been active in the application of enhanced optical transmission to chemical and biological sensing, and in the optofluidic integration nanohole arrays. Our recent work in this area is described here. Our research on the combined photonic and fluidic characteristics of flow-through nanohole arrays and their application to sensing is presented. Flow-through nanohole arrays provide a biomarker sieving capacity that is unique among plasmonic sensors as well as rapid transport of reactants to the sensing surface. Our experiments indicate a order of magnitude improvement in sensor response time for flow-through operation as compared to current flow-over sensing methods. Transport analysis results indicate that more than a 20-fold improvement may be expected for small biomolecules with rapid reaction kinetics.

Citation Download Citation

Carlos Escobedo, Alexandre G. Brolo, Reuven Gordon, and David Sinton "Nanoplasmonics as nanofluidics: transport and sensing in flowthrough nanohole arrays", Proc. SPIE 7929, Microfluidics, BioMEMS, and Medical Microsystems IX, 79290Q (14 February 2011); https://doi.org/10.1117/12.875848

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