High-speed high-resolution OCT imaging of the retina with frequency swept lasers at 850 nm

V. J. Srinivasan; R. Huber; I. Gorczynska; D. Adler; J. Y. Jiang; P. Reisen; A. E. Cable; J. G. Fujimoto

doi:10.1117/12.699433

5 March 2007 High-speed high-resolution OCT imaging of the retina with frequency swept lasers at 850 nm

V. J. Srinivasan, R. Huber, I. Gorczynska, D. Adler, J. Y. Jiang, P. Reisen, A. E. Cable, J. G. Fujimoto

Proceedings Volume 6426, Ophthalmic Technologies XVII; 642603 (2007) https://doi.org/10.1117/12.699433
Event: SPIE BiOS, 2007, San Jose, California, United States

Abstract

Ophthalmic OCT was performed using a novel, compact external cavity semiconductor laser at ~850 nm. Retinal imaging was demonstrated with a resolution of <7 microns in tissue at a speed of 16,000 axial scans per second. The coherence length of the laser is >10 mm, enabling an axial measurement range of ~2.5 mm. Real-time display and data streaming capabilities enable video-rate imaging of the retina at >30 frames per second. High-definition and three-dimensional imaging were demonstrated on normal retinas. The resolution of <7 microns in the retina is, to our knowledge, the highest resolution achieved in the retina with swept source OCT to date. The long coherence length of the laser enables high-sensitivity measurements over a large axial measurement range. The speed of 16,000 axial scans per second is comparable to current spectrometer-based spectral/Fourier domain OCT systems. The low cost and small footprint of our laser (~10 cm x 20 cm) may enable the development of OCT for novel applications. Further improvements in speed will be possible by using alternative scanning methods.

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V. J. Srinivasan, R. Huber, I. Gorczynska, D. Adler, J. Y. Jiang, P. Reisen, A. E. Cable, and J. G. Fujimoto "High-speed high-resolution OCT imaging of the retina with frequency swept lasers at 850 nm", Proc. SPIE 6426, Ophthalmic Technologies XVII, 642603 (5 March 2007); https://doi.org/10.1117/12.699433

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KEYWORDS

Optical coherence tomography

Retinal scanning

Retina

Image resolution

Image segmentation

Imaging systems

Spectroscopy

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