Fluorescent and photodynamic properties of infrared photosensitizer bacteriochlorophyllide-serine

I. G. Meerovich; Irina Yu. Kubasova; Gennadii A. Meerovich; Alexander A. Stratonnikov; S. A. Demura; Alexandr S. Brandis; V. Rosenbach-Belkin; Avigdor Scherz

doi:10.1117/12.563144

21 June 2004 Fluorescent and photodynamic properties of infrared photosensitizer bacteriochlorophyllide-serine

I. G. Meerovich, Irina Yu. Kubasova, Gennadii A. Meerovich, Alexander A. Stratonnikov, S. A. Demura, Alexandr S. Brandis, V. Rosenbach-Belkin, Avigdor Scherz

Author Affiliations +

Proceedings Volume 5449, Eighth International Conference on Laser and Laser Information Technologies; (2004) https://doi.org/10.1117/12.563144
Event: Eighth International Conference on Laser and Laser Information Technologies, 2003, Smolyan, Bulgaria

Abstract

The study is devoted to investigation of fluorescent and photodynamic properties of near-infrared photosensitizer bacteriochlorophyllide-serine. The peculiarities of its fluorescence under different laser excitation conditions, dynamics of concentration and selectivity of accumulation were investigated. Photodynamic therapy of mice and investigation of tissue deoxygenation during tumor irradiation were performed. It was shown that bacteriochlorophyllide-serine is an effective photosensitizer for PDT and fluorescent diagnostics of tumors.

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I. G. Meerovich, Irina Yu. Kubasova, Gennadii A. Meerovich, Alexander A. Stratonnikov, S. A. Demura, Alexandr S. Brandis, V. Rosenbach-Belkin, and Avigdor Scherz "Fluorescent and photodynamic properties of infrared photosensitizer bacteriochlorophyllide-serine", Proc. SPIE 5449, Eighth International Conference on Laser and Laser Information Technologies, (21 June 2004); https://doi.org/10.1117/12.563144

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