Handheld low-frequency phased array near-infrared (NIR) breast cancer localizer

Qian Liu; Yu Chen; Qingming Luo

doi:10.1117/12.503168

29 July 2003 Handheld low-frequency phased array near-infrared (NIR) breast cancer localizer

Qian Liu, Yu Chen, Qingming Luo

Proceedings Volume 4955, Optical Tomography and Spectroscopy of Tissue V; (2003) https://doi.org/10.1117/12.503168
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

A system for rapid and precise localization of breast cancer using low frequency phased array near-infrared technique has been developed. In this system, in-phase and out-of-phase of sine-wave signals at 3 kHz modulate two light emitting diode (LED) sources respectively. And amplitude cancellation of two photon density waves will occur in the silicon-detector at the mid-plane of two sources reference. Cancellation signal is displayed by an embedded amplitude and phase detector and is displayed acoustically. The whole system is pocket-size, handheld with the dimension of 6.0cm×5.0cm×2.5cm and the weight is 140g. Experiments with phantom and animals show that the system can provide real time detection and localization of small hidden absorbing-fluorescent objects inside the highly scattering medium at the depth of 2cm with high accuracy of ±1 ~ 2mm. The limit of object detection with 20 mA LED current is 1cm and with 40 mA is 2cm. The potential application is that it can be used for early breast cancer detection as a convenient self-examination device.

Citation Download Citation

Qian Liu, Yu Chen, and Qingming Luo "Handheld low-frequency phased array near-infrared (NIR) breast cancer localizer", Proc. SPIE 4955, Optical Tomography and Spectroscopy of Tissue V, (29 July 2003); https://doi.org/10.1117/12.503168

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