Ultrahigh-resolution optical coherence tomography for enhanced visualization of retinal pathology

Tony H. Ko; Wolfgang Drexler; Lelia Adelina Paunescu; Ingmar Hartl; Ravi K. Ghanta; Joel S. Schuman; James G. Fujimoto

doi:10.1117/12.479032

8 July 2003 Ultrahigh-resolution optical coherence tomography for enhanced visualization of retinal pathology

Tony H. Ko, Wolfgang Drexler, Lelia Adelina Paunescu, Ingmar Hartl, Ravi K. Ghanta, Joel S. Schuman, James G. Fujimoto

Proceedings Volume 4956, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VII; (2003) https://doi.org/10.1117/12.479032
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

An ultrahigh resolution ophthalmic optical coherence tomography (OCT) system has been developed. Using a femtosecond Ti:sapphire laser light source, which generates bandwidths of ~150 nm at 800 nm, real-time, cross-sectional imaging of the retina with ~3 μm axial resolution is possible. Ultrahigh resolution OCT images of retinal morphology were obtained in normal subjects and patients with retinal disease. Intraretinal architectural morphology associated with macular diseases such as macular edema, epiretinal membranes, and macular holes can be visualized with unprecedented resolution. Ultrahigh resolution ophthalmic OCT promises to improve the early diagnosis of retinal diseases as well as enable monitoring of disease progression and the efficacy of therapeutic intervention.

Citation Download Citation

Tony H. Ko, Wolfgang Drexler, Lelia Adelina Paunescu, Ingmar Hartl, Ravi K. Ghanta, Joel S. Schuman, and James G. Fujimoto "Ultrahigh-resolution optical coherence tomography for enhanced visualization of retinal pathology", Proc. SPIE 4956, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine VII, (8 July 2003); https://doi.org/10.1117/12.479032

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