Novel bonding method for polymer-based microfluidic platforms

Siyi Lai; Yeny Hudiono; Ly James Lee; Sylvia Daunert; Marc J. Madou

doi:10.1117/12.442956

28 September 2001 Novel bonding method for polymer-based microfluidic platforms

Siyi Lai, Yeny Hudiono, Ly James Lee, Sylvia Daunert, Marc J. Madou

Proceedings Volume 4557, Micromachining and Microfabrication Process Technology VII; (2001) https://doi.org/10.1117/12.442956
Event: Micromachining and Microfabrication, 2001, San Francisco, CA, United States

Abstract

Polymer-based microfluidic platforms have great potential for use in BioMEMS applications because many polymers are low cost, biocompatible, and have good processibility. However, packaging (i.e., sealing the platform with a lid) is a challenging issue in their fabrication. In this paper, we compare several available bonding techniques such as adhesive tape bonding and chemical-assisted bonding with a new method recently developed in our lab: resin-gas injection-assisted bonding. This new approach can easily seal microfluidic devices with micron and sub-micron sized channels without blocking the flow path. It can also be used to modify the channel shape, size, and surface characteristics (e.g., hydrophilicity, degree of protein adsorption). By applying the masking technique, local modification of the channel surface can be achieved through cascade resin-gas injection. Experiments are carried out to demonstrate the bonding efficiency and surface modification.

Citation Download Citation

Siyi Lai, Yeny Hudiono, Ly James Lee, Sylvia Daunert, and Marc J. Madou "Novel bonding method for polymer-based microfluidic platforms", Proc. SPIE 4557, Micromachining and Microfabrication Process Technology VII, (28 September 2001); https://doi.org/10.1117/12.442956

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