Paper
24 April 1998 New ways to observe and control dynamics
Kent R. Wilson, Chris J. Bardeen, Christopher P. P. Barty, G. J. Brakenhoff, Arjan H. Buist, Jianshu Cao, Scott D. Carpenter, Jian Wei Che, David N. Fittinghoff, Michiel Mueller, Jeffrey A. Squier, Warren S. Warren, Peter M. Weber, Vladislav V. Yakovlev
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Abstract
We summarize recent progress aimed at observing biochemical and biological dynamics using confocal microscopy with 3D spatial resolution down to a few hundred nm and temporal resolution to 15 fs. We also review recent control of population dynamics using tailored ultrafast pulses, i.e. quantum control. Progress is described for i) feedback control, ii) multiphoton control, and iii) molecular (pi) pulse. Finally, using ultrafast light pulses, we combine confocal and quantum control techniques to produce a new way to measure the microscopy chemical environment, int his case pH, potentially with a spatial resolution of a few hundred nanometers.
© (1998) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Kent R. Wilson, Chris J. Bardeen, Christopher P. P. Barty, G. J. Brakenhoff, Arjan H. Buist, Jianshu Cao, Scott D. Carpenter, Jian Wei Che, David N. Fittinghoff, Michiel Mueller, Jeffrey A. Squier, Warren S. Warren, Peter M. Weber, and Vladislav V. Yakovlev "New ways to observe and control dynamics", Proc. SPIE 3273, Laser Techniques for Condensed-Phase and Biological Systems, (24 April 1998); https://doi.org/10.1117/12.306130
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Cited by 1 scholarly publication.
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KEYWORDS
Confocal microscopy

Spatial resolution

Ultrafast phenomena

Environmental sensing

Feedback control

Microscopy

Multiphoton microscopy

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