Thermophoretic trapping and manipulation of single molecules

Marco Braun; Tobias Thalheim; Katrin Günther; Michael Mertig; Frank Cichos

doi:10.1117/12.2239481

23 November 2016 Thermophoretic trapping and manipulation of single molecules

Marco Braun, Tobias Thalheim, Katrin Günther, Michael Mertig, Frank Cichos

Proceedings Volume 9922, Optical Trapping and Optical Micromanipulation XIII; 99220Z (2016) https://doi.org/10.1117/12.2239481
Event: SPIE Nanoscience + Engineering, 2016, San Diego, California, United States

Abstract

We demonstrate the long time trapping of single DNA molecules in liquids by feedback driven dynamic temperature fields. By spatially and temporally varying the temperature at a plasmonic nanostructure, thermophoretic drifts are induced that are used to trap single nano-objects. A feedback controlled switching of local temperature fields allows us to confine the motion of a single DNA molecule for minutes. The DNA conformation and conformation dynamics are analyzed in terms of a principle component analysis. Current results are in agreement with previous measurements in thermal equilibrium and suggest only a weak influence of the inhomogeneous temperature rise on the structure and dynamics in the trap.

Conference Presentation

Citation Download Citation

Marco Braun, Tobias Thalheim, Katrin Günther, Michael Mertig, and Frank Cichos "Thermophoretic trapping and manipulation of single molecules", Proc. SPIE 9922, Optical Trapping and Optical Micromanipulation XIII, 99220Z (23 November 2016); https://doi.org/10.1117/12.2239481

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