Integrated microfluidic spectroscopic sensor using arrayed waveguide grating

Zhixiong Hu; Andrew Glidle; Charles N. Ironside; Marc Sorel; Michael Strain; Jonathan M. Cooper; Huabing Yin

doi:10.1117/12.2033213

23 August 2013 Integrated microfluidic spectroscopic sensor using arrayed waveguide grating

Zhixiong Hu, Andrew Glidle, Charles N. Ironside, Marc Sorel, Michael Strain, Jonathan M. Cooper, Huabing Yin

Proceedings Volume 8911, International Symposium on Photoelectronic Detection and Imaging 2013: Micro/Nano Optical Imaging Technologies and Applications; 89110A (2013) https://doi.org/10.1117/12.2033213
Event: ISPDI 2013 - Fifth International Symposium on Photoelectronic Detection and Imaging, 2013, Beijing, China

Abstract

With non-invasive properties and high sensitivities, portable optical biosensors are extremely desirable for point-of-care (POC) applications. Lab-on-a-chip technology such as microfluidics has been treated as an ideal approach to integrate complex sample processing and analysis units with optical detection elements. The work in this paper has developed an integrated dispersive component in combination with a microfluidic chip, providing a portable and inexpensive platform for on-chip spectroscopic sensing. We demonstrate an integrated microfluidic spectroscopic sensor by using an arrayed waveguide grating (AWG) device. In particular, a visible AWG device (λ_c=680nm) with chip size of 12.1mm by 1.5mm was designed and fabricated by employing flamed hydrolysis deposited (FHD) silica as the waveguide material. A straight input waveguide is used to perform device characterization while a perpendicular curved waveguide is employed to introduce laser excitation light. A polymer microfluidic chip is integrated with the AWG device by oxygen plasma bonding. To prove effectiveness of the integrated spectroscopic sensor, fluorescence spectrum of an organic fluorophore (Cy5) was tested. Reconstructed spectrum by using the AWG device is compared with the outcome from a conventional spectrometer and a good consistency is presented.

Citation Download Citation

Zhixiong Hu, Andrew Glidle, Charles N. Ironside, Marc Sorel, Michael Strain, Jonathan M. Cooper, and Huabing Yin "Integrated microfluidic spectroscopic sensor using arrayed waveguide grating", Proc. SPIE 8911, International Symposium on Photoelectronic Detection and Imaging 2013: Micro/Nano Optical Imaging Technologies and Applications, 89110A (23 August 2013); https://doi.org/10.1117/12.2033213

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available