Optical monitoring of chemical reactions by fluorescence in turbid media

Steven L. Jacques

doi:10.1117/12.147693

7 July 1993 Optical monitoring of chemical reactions by fluorescence in turbid media

Steven L. Jacques

Proceedings Volume 1882, Laser-Tissue Interaction IV; (1993) https://doi.org/10.1117/12.147693
Event: OE/LASE'93: Optics, Electro-Optics, and Laser Applications in Scienceand Engineering, 1993, Los Angeles, CA, United States

Abstract

The observation of fluorescence in a tissue offers a method of real-time monitoring of chemical reactions when one of the reagents or products in fluorescent. This paper discusses how tissue optics affects one's observation of fluorescence in a turbid medium such as tissue. An experimental example is also shown: the photobleaching of a photosensitizer molecule (protoporphyrin IX) within rat tumors. A simple algorithm (Gardner et al., 1993) is given which enables the corrections for tissue optics.

Citation Download Citation

Steven L. Jacques "Optical monitoring of chemical reactions by fluorescence in turbid media", Proc. SPIE 1882, Laser-Tissue Interaction IV, (7 July 1993); https://doi.org/10.1117/12.147693

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