ORIGINAL ARTICLEEx vivo allotransplantation engineering: Delivery of mesenchymal stem cells prolongs rejection-free allograft survival
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KEYWORDS
animal models: murine
basic (laboratory) research/science
immunosuppression/immune modulation
organ transplantation in general
rejection
stem cells
tolerance: experimental
tolerance: mechanisms
translational research/science
vascularized composite and reconstructive transplantation
Abbreviations
BMSC
bone marrow–derived mesenchymal stem cell
EC
endothelial cell
IDO
indoleamine 2,3-dioxygenase
IFN
interferon
iNOS
inducible nitric oxide synthase
IRI
ischemia–reperfusion injury
MSC
mesenchymal stem cell
PFA
paraformaldehyde
SDF1α
stromal cell–derived factor 1α
TGF
transforming growth factor
TNF
tumor necrosis factor
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Marc A. Soares and Jonathan P. Massie contributed equally to the manuscript and project.
Copyright © 2018 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. Published by Elsevier B.V. All rights reserved.