Dynamics of Specific Vesicle-Substrate Adhesion: From Local Events to Global Dynamics

Ellen Reister-Gottfried, Kheya Sengupta, Barbara Lorz, Erich Sackmann, Udo Seifert, and Ana-Sunčana Smith
Phys. Rev. Lett. 101, 208103 – Published 13 November 2008
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Abstract

We present a synergistic combination of simulations and experimental data on the dynamics of membrane adhesion. We show that a change in either the density or the strength of the bonds results in very different dynamics. Such behavior is explained by introducing an effective binding affinity that emerges as a result of the competition between the strength of the chemical bonds and the environment defined by the fluctuating membrane.

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  • Received 30 April 2008

DOI:https://doi.org/10.1103/PhysRevLett.101.208103

©2008 American Physical Society

Authors & Affiliations

Ellen Reister-Gottfried1, Kheya Sengupta2, Barbara Lorz3, Erich Sackmann3, Udo Seifert1, and Ana-Sunčana Smith1,*

  • 1II. Institut für Theoretische Physik, Universität Stuttgart, D-70550 Stuttgart, Germany
  • 2Centre Interdisciplinaire de Nanosciences de Marseille (CINaM/CNRS-UPR3118), Marseille Cedex 9, France
  • 3E22 Institut für Biophysik, Technische Universität München, D-85748 Garching, Germany

  • *Corresponding author.

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Issue

Vol. 101, Iss. 20 — 14 November 2008

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