RNA Interference, Heterochromatin, and Centromere Function
This extract was created in the absence of an abstract.
Excerpt
The centromere regions of most eukaryotic metaphasechromosomes are distinctive. The narrower, more compact appearance of these regions reflects two importantrelated features: centromeric cohesion and extensiveblocks of heterochromatin. First, sister centromeres remain associated because the cohesin complex remains intact at centromeres until anaphase. Second, the chromatincoating these regions is very different since they remaincondensed throughout the cell cycle and are clearly visible as the most concentrated foci of DNA in interphasecells; this has been termed heterochromatin (Bernard andAllshire 2002)...
