Ensembl: A Genome Infrastructure
This extract was created in the absence of an abstract.
Excerpt
The genome sequence of any organism is an invaluableresource for molecular biologists. Experiments are eithertrivial to design or greatly enhanced by the knowledge ofthe genome sequence; linkage analysis leads directly to aset of genes in the critical region, and association studiescan be designed to any region (including, in theory, theentire genome). At least as important as the ease of experimental design is the fact that the genome is essentially complete, and therefore, researchers can be confident that the aspects of biology they are studying must bepresent in the genome sequence in some manner. The factthat all biology is somehow associated with some aspectof the genome, that the genome is complete and essentially unchanging, means that it is a foundational resourcefor biology. The generation of the human (Landfer et al.2001) and mouse (Waterston et al. 2002) genome sequences provided landmarks for the understanding of human biology...
