The Sarcoglycan Complex in Striated and Vascular Smooth Muscle
This extract was created in the absence of an abstract.
Excerpt
Congestive heart failure (CHF), a leading cause of hospitalization and death, arises when cardiac output is insufficient to meet demand. Cardiomyopathy, defined asdysfunction of cardiac muscle, frequently results in CHFand may arise as a consequence of ischemic, toxic, immunologic, or genetic insult. Decompensated cardiomyopathy may occur as a result of progressive ventriculardysfunction and is often aggravated by cardiac arrhythmias. Understanding the molecular and physiologicalmechanisms that underlie cardiomyopathy progression iscentral to improving treatment options...
