The DPE, a Conserved Downstream Core Promoter Element That Is Functionally Analogous to the TATA Box

  1. T.W. BURKE,
  2. P.J. WILLY,
  3. A.K. KUTACH,
  4. J.E.F. BUTLER, and
  5. J.T. KADONAGA
  1. Department of Biology, 0347, and Center for Molecular Genetics, University of California, San Diego, La Jolla, California 92093-0347

This extract was created in the absence of an abstract.

Excerpt

Transcription by RNA polymerase II is a fundamentaland important biological process. There are tens of thousands of diverse genes that are transcribed in a highly regulated manner by the RNA polymerase II transcriptionalmachinery, and thus the mechanisms by which transcription is controlled are necessarily complex (for reviews,see Conaway and Conaway 1993; Smale 1994; Koleskeand Young 1995; Zawel and Reinberg 1995; Björklundand Kim 1996; Kaiser and Meisterernst 1996; Orphanides et al. 1996; Reines et al. 1996; Roeder 1996;Svejstrup et al. 1996; Verrijzer and Tjian 1996)...

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