Ribosomal Genes and Their Proteins from Xenopus
This extract was created in the absence of an abstract.
Excerpt
For the past several years our laboratory has been studying the structure and function of the genes coding for 18S and 28S rRNA from the frog Xenopus. In this article we will summarize two recent developments from this work. One development is the use of a novel procedure for identifying the 5′ termini of primary transcripts from rDNA. This is a procedure that should have wide application for the study of other genes in addition to rDNA. A second area we will discuss is the isolation of highly purified rDNA chromatin and the initial characterization of the proteins that are associated with it. Other studies concerning the arrangement of repetitive DNA sequences in the nontranscribed spacer have been published recently (Botchan et al. 1977) and will not be discussed in this article.
RNA CHAIN INITIATION SITES ON RIBOSOMAL DNA
The size of the primary transcription product is still unknown for...
