Stage-Specific RNA Transcription in Developing Sea Urchins and Their Chromatins
This extract was created in the absence of an abstract.
Excerpt
It is well known that the messenger RNA (mRNA) populations of developing sea urchins display a systematic departure from the maternal mRNA present in the unfertilized egg that is characterized by a retention of much of the maternal mRNA into the prism larva stage and the gradual appearance of new varieties of mRNA which becomes particularly marked after the hatching blastula stage (Glisin, Glisin, and Doty, 1966; Whiteley, McCarthy, and Whiteley, 1966). These patterns evidently have their origin in differential gene transcription and probably to a lesser degree in differential mRNA degradation. With the more recent demonstration of organ-specific transcription and the persistence of these specifities in the chromatin of the corresponding organs (Paul and Gilmour, 1968) it became of interest to see if the chromatin from different developmental stages also displayed a specific transcription. If so, this would mean that many of the controls of successive developmental stages were...
