Summary: Molecular Biology of Viral Oncogenes
This extract was created in the absence of an abstract.
Excerpt
In 1974, many of us attended the Cold Spring Harbor Laboratory Symposium on the molecular biology of tumor viruses. That Symposium codified a number of advances in the study of these viruses and provided a foundation for further developments in this field, In his summary of the papers presented at that Symposium, Baltimore (1975) suggested that the groundwork for the molecular biology of tumor viruses was almost finished, and advances in our understanding of how these viruses cause tumors would soon begin. This, in fact, is the subject of the 1979 Symposium: viral oncogenes. Again, the molecular biology of tumor viruses was the main topic of discussion; however, emphasis was placed on the origin, structure, and protein products of virus-associated genes that affect cell proliferation. Surprisingly, there was little discussion of possible mechanisms by which viral oncogenes transform mammalian cells. This must await further developments in cell biology and virology...
