Pavlovian influences on goal-directed behavior in mice: The role of cue-reinforcer relations
Abstract
Two experiments refined procedures to study Pavlovian influences on goal-directed behavior in mice and studied the effects of CS–US relations in Pavlovian-instrumental interactions. Independent groups of mice underwent Pavlovian training to associate either a 10-sec or 2-min auditory stimulus (CS) with reward. We next assessed the ability of the response-contingent CS presentations to reinforce novel instrumental responding (conditioned reinforcement; CRf) or the ability of noncontingent CS presentations to increase ongoing instrumental responding (Pavlovian-instrumental transfer; PIT). Whereas 10-sec training conditions produced strong CRf (and no PIT), 2-min training conditions produced robust PIT (but no CRf).
Footnotes
-
↵3 Corresponding author.
↵3 E-mail h.crombag{at}sussex.ac.uk; fax (410) 516-0494.
-
Article is online at http://www.learnmem.org/cgi/doi/10.1101/lm.762508.
-
- Received September 4, 2007.
- Accepted March 7, 2008.
- Copyright © 2008, Cold Spring Harbor Laboratory Press