RNAi genes pave their own way
Abstract
Heterochromatin formation in fission yeast and the role of RNAi in this process have been intensively studied. So far, however, nothing is known about the regulation of expression of RNAi components during these events. Gullerova and colleagues (pp. 556–568) reveal an autoregulatory loop that regulates the expression of RNAi genes and centromeric heterochromatin formation during the cell cycle. Gene orientation plays a surprising role in this process.
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Footnotes
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↵1 Corresponding author.
E-MAIL r.ketting{at}hubrecht.eu; FAX 31-030-2516554.
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Article is online at http://www.genesdev.org/cgi/doi/10.1101/gad.2038611.
- Copyright © 2011 by Cold Spring Harbor Laboratory Press
