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Experimental Modeling in Biology: In Vivo Representation and Stand-Ins as Modeling Strategies

Published online by Cambridge University Press:  01 January 2022

Abstract

Experimental modeling in biology involves the use of living organisms (not necessarily so-called model organisms) in order to model or simulate biological processes. I argue here that experimental modeling is a bona fide form of scientific modeling that plays an epistemic role that is distinct from that of ordinary biological experiments. What distinguishes them from ordinary experiments is that they use what I call “in vivo representations,” where one kind of causal process is used to stand in for a physically different kind of process. I discuss the advantages of this approach in the context of evolutionary biology.

Type
Signaling Theory in Biological and Cognitive Sciences
Copyright
Copyright © The Philosophy of Science Association

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Footnotes

I wish to thank Kristina Hillesland, Mike Travisano, Ken Waters, and the San Diego audience for an exciting PSA 2012 Symposium on experimental modeling. This paper also benefited from discussion with audiences at the Ludwig Maximilian University of Munich, the Sorbonne, and the Second European Advanced Seminar in the Philosophy of the Life Sciences (Hermance).

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